Protein Alignment Hsc70-4 and lsh1

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_592867.1
• Gene: lsh1 / 2541537
• PomBaseID: SPAC1F5.06
• Length: 848
• Species: Schizosaccharomyces pombe
• Alignment Length: 682
• Identity: 177/682 - (25%)
• Similarity: 297/682 - (43%)
• Gaps: 101/682 - (14%)

  Fly     7 VGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDA 70
            :.||.||.::...:.:.| .:||:......|...|.|||...||:.|..|.|.....|..:|.:.
pombe    25 LAIDYGTEWTKAALIKPGIPLEIVLTKDTRRKEQSAVAFKGNERIFGVDASNLATRFPAHSIRNV 89

  Fly    71 KRLIGRKFDDAAVQSDM--KHWPFEVVSADGKPKIEVTYKDE-----------KKTFFPEEISSM 122
            |.|:    |.|.::|.:  |:       ....|.|::...:|           ::.:..|||.:|
pombe    90 KELL----DTAGLESVLVQKY-------QSSYPAIQLVENEETTSGISFVISDEENYSLEEIIAM 143

  Fly   123 VLTKMKETAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDK 187
            .:......||....:.:|:.|:|||.:||:.||....:|..|...:||.:|::..|.||.|.|.:
pombe   144 TMEHYISLAEEMAHEKITDLVLTVPPHFNELQRSILLEAARILNKHVLALIDDNVAVAIEYSLSR 208

  Fly   188 K-AVGERNVLIFDLGGGTFDVSILSID----------DGIFEVKSTA-GDT-HLGGEDFDNRLVT 239
            . :......:|:|.|.|:...:::|.|          ..|..:::.| |.| .|.|.:.:.:|:.
pombe   209 SFSTDPTYNIIYDSGSGSTSATVISFDTVEGSSLGKKQNITRIRALASGFTLKLSGNEINRKLIG 273

  Fly   240 HFVQEFKRKHKKDLTTNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEE 304
            .....|.:||..||:.|.|||.||.....|.|..||::::|...|:.|.:|.||...|||:..|.
pombe   274 FMKNSFYQKHGIDLSHNHRALARLEKEALRVKHILSANSEAIASIEELADGIDFRLKITRSVLES 338

  Fly   305 LNADLFRSTMDPVEKALRDAKLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAV 369
            |..|:..:.::|:.|||:.|.|..|.|:.|:|.||::|||.:|..|.|..:..:::|::|.|||.
pombe   339 LCKDMEDAAVEPINKALKKANLTFSEINSIILFGGASRIPFIQSTLADYVSSDKISKNVNADEAS 403

  Fly   370 AYGAAVQAAILHGDKSQEVQDLLLLDVT--PLSLGIETAGGVMSVL------IKRNTTIPTKQTQ 426
            ..|||...|.|  .||..|:.|::.|:.  |..|.:.|:..::::.      ::.|.||....|
pombe   404 VKGAAFYGASL--TKSFRVKPLIVQDIINYPYLLSLGTSEYIVALPDSTPYGMQHNVTIHNVST- 465

  Fly   427 TFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELSGIPPAPR----GVPQIEVTFDID-ANGIL 486
                 ....|..         .::.:..|:|:|.||.|....:    ....|:::|..| ..|||
pombe   466 -----IGKHPSF---------PLSNNGELIGEFTLSNITDVEKVCACSNKNIQISFSSDRTKGIL 516

  Fly   487 ----------------------NVTALERS-------TNKENKITITNDK-GRLSKEDIERMVNE 521
                                  .|.:|..|       .|:...|..|..| |.:|...:.....:
pombe   517 VPLSAIMTCEHGELSSKHKLGDRVKSLFGSHDESGLRNNESYPIGFTYKKYGEMSDNALRLASAK 581

  Fly   522 AEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCN-ETIKWL-DAN 584
            .|:....|:.:.....|.|.||:..:..:|.:|:|.. .:.::.:.|.||...: |:..|| :..
pombe   582 LERRLQIDKSKAAHDNALNELETLLYRAQAMVDDDEF-LEFANPEETKILKNDSVESYDWLIEYG 645

  Fly   585 QLADKEEYEHRQKELEGVCNPIITKLYQGAGF 616
            ..:...|...|.|:|:.....|..:..|...|
pombe   646 SQSPTSEVTDRYKKLDDTLKSISFRFDQAKQF 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	175/676 (26%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	120/400 (30%)
lsh1	NP_592867.1	DnaK	19..667	CDD:223520	174/670 (26%)
		HYOU1-like_NBD	25..412	CDD:212672	119/397 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910