Protein Alignment Hsc70-4 and sks2

DIOPT Version :10

• Sequence 1: NP_524356.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_595438.1
• Gene: sks2 / 2540199
• PomBaseID: SPBC1709.05
• Length: 613
• Species: Schizosaccharomyces pombe
• Alignment Length: 583
• Identity: 359/583 - (61%)
• Similarity: 445/583 - (76%)
• Gaps: 4/583 - (0%)

  Fly     6 AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDA 70
            |:|||||||||||.|::...||||.||||.|||||:||||:||||:|||||||.||||..|:|||
pombe     8 AIGIDLGTTYSCVAVWETANVEIIPNDQGARTTPSFVAFTETERLVGDAAKNQAAMNPRNTVFDA 72

  Fly    71 KRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAYL 135
            ||||||:::|...|.|:|||||:|:..:|.|.|||.|..|||.|..:|||:||||||||.:||.|
pombe    73 KRLIGRRYEDPETQKDIKHWPFKVIDNNGIPTIEVNYLGEKKQFTAQEISAMVLTKMKEISEAKL 137

  Fly   136 GKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNVLIFDL 200
            .|.|..|||||||||:||||.||||||.|||||||||||||||||||||||.|:...:|||||||
pombe   138 NKRVEKAVITVPAYFSDSQRAATKDAGAIAGLNVLRIINEPTAAAIAYGLDAKSDKPKNVLIFDL 202

  Fly   201 GGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRRLRT 265
            ||||||||:|.|..|:|||.:||||||||||||||.||.||:||||||.|.|::.:.|||||||:
pombe   203 GGGTFDVSLLKIQGGVFEVLATAGDTHLGGEDFDNALVEHFIQEFKRKQKIDISDDPRALRRLRS 267

  Fly   266 ACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKLDKSV 330
            |||||||.|||.||.::|:|||..|.||.:||||||||::||..|::|:|||.|.|:|:|:.|:.
pombe   268 ACERAKRALSSVTQTTVEVDSLSNGIDFSSSITRARFEDINATTFKATIDPVAKVLKDSKVPKAD 332

  Fly   331 IHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAIL-HGDKSQEVQDLLLL 394
            :||||||||||||||||||:.|.|:|:.||||||||||||||||||||:| :...|.:.||||||
pombe   333 VHDIVLVGGSTRIPKVQRLVSDFFDGRALNKSINPDEAVAYGAAVQAAVLTNKADSDKTQDLLLL 397

  Fly   395 DVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKF 459
            ||.|||||:...|.|..|:..|||.|||.:.:||||.:|||..|...||:|||....:|..||:|
pombe   398 DVVPLSLGVAMEGNVFGVVCPRNTPIPTIKKRTFTTVADNQTTVTFPVYQGERVNCAENEPLGEF 462

  Fly   460 ELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVNEAEK 524
            :|:||||.|||..::|.||::||||||.|||:|::|.:...|.|||..|.||...|:.|:..|:|
pombe   463 QLTGIPPMPRGQAELEATFELDANGILKVTAVEKTTGRSAHIEITNSVGHLSSTKIQEMIENADK 527

  Fly   525 YRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTI---LDKCNETIKWLDAN 584
            ::.:|:...:.:.||:.||||..|::.|:.|.|:..|:...|::.|   |.:|...::..|.|
pombe   528 FKQQDKDFAKKLEAKSQLESYISNIETTISEPNVMMKLKRGDKSKIEAQLAECMSQLELEDTN 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_524356.1	PTZ00009	1..612	CDD:240227	359/583 (62%)
sks2	NP_595438.1	PTZ00009	5..585	CDD:240227	357/576 (62%)