Protein Alignment Hsc70-4 and DENND6A

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_689891.1
• Gene: DENND6A / 201627
• HGNCID: 26635
• Length: 608
• Species: Homo sapiens
• Alignment Length: 191
• Identity: 42/191 - (21%)
• Similarity: 70/191 - (36%)
• Gaps: 51/191 - (26%)

  Fly     7 VGIDLGTTYSCVGVF-QHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDA 70
            ||.||....:...:: ||.|:    .|: .:|...|::|.|:         |...:..||..|..
Human    68 VGFDLELGQAVEVIYPQHSKL----TDR-EKTNICYLSFPDS---------NSGCLGDTQFCFRF 118

  Fly    71 KRLIGRK---------FD-DAAV--QSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMV 123
            ::..||:         || |..|  :.|..::...|...      :|..|..|:.:|.:   |:|
Human   119 RQSSGRRVSLHCLLDQFDKDLPVYLKKDPAYFYGYVYFR------QVRDKTLKRGYFQK---SLV 174

  Fly   124 L-----------TKMKETAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRII 173
            |           |.:|:.|..|..|...    .:.|..||..|......|....|.::.::
Human   175 LISKLPYIHFFHTVLKQIAPEYFEKNEP----YLEAACNDVDRWPAPVPGKTLHLPIMGVV 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	42/191 (22%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	42/191 (22%)
DENND6A	NP_689891.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48
		Avl9	64..>201	CDD:331426	36/155 (23%)
		DENN	171..359	CDD:325068	14/68 (21%)
		SPA	270..373	CDD:312210

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910