Protein Alignment Hsc70-4 and hsp-4

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001370395.1
• Gene: hsp-4 / 174203
• WormBaseID: WBGene00002008
• Length: 657
• Species: Caenorhabditis elegans
• Alignment Length: 612
• Identity: 375/612 - (61%)
• Similarity: 483/612 - (78%)
• Gaps: 6/612 - (0%)

  Fly     7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT--DTERLIGDAAKNQVAMNPTQTIFD 69
            :||||||||||||||::|:|||||||||||.|||||||:  ..|||||||||||:.:||..||||
 Worm    33 IGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFSGDQGERLIGDAAKNQLTINPENTIFD 97

  Fly    70 AKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAY 134
            |||||||.:::..||.|:|||||::|....||.:||....|.|.|.|||:|:|||||||:.||:|
 Worm    98 AKRLIGRFYNEKTVQQDIKHWPFKIVDKSNKPNVEVKVGSETKQFTPEEVSAMVLTKMKQIAESY 162

  Fly   135 LGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNVLIFD 199
            ||..|.|||:||||||||:|:|||||||:||||||:||||||||||||||||||. ||||:|:||
 Worm   163 LGHEVKNAVVTVPAYFNDAQKQATKDAGSIAGLNVVRIINEPTAAAIAYGLDKKD-GERNILVFD 226

  Fly   200 LGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRRLR 264
            |||||||||:|:||.|:|||.:|.|||||||||||.|::.:|::.:|:|..|||..:.||:::||
 Worm   227 LGGGTFDVSLLTIDSGVFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDNRAVQKLR 291

  Fly   265 TACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKLDKS 329
            ...|:|||.||:..|..|||:|||:|.||..::|||:|||||.||||:|:.||:|.|.||.:.|:
 Worm   292 REVEKAKRALSTQHQTKIEIESLFDGEDFSETLTRAKFEELNMDLFRATLKPVQKVLEDADMKKT 356

  Fly   330 VIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQDLLLL 394
            .:|:||||||||||||||:|::|.|||||.::.|||||||||||||||.::.|  .:...|::||
 Worm   357 DVHEIVLVGGSTRIPKVQQLIKDYFNGKEPSRGINPDEAVAYGAAVQAGVIGG--VENTGDVVLL 419

  Fly   395 DVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKF 459
            ||.||:|||||.||||:.||.|||.||||::|.|:|.:|:|..|.|.:|||||.|..||:.||.|
 Worm   420 DVNPLTLGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADSQSAVSIVIYEGERPMVMDNHKLGNF 484

  Fly   460 ELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVNEAEK 524
            :::||||||||||||||||:||.||||:|:|.::.|..:||:|||||..|||.||||||:|:|:|
 Worm   485 DVTGIPPAPRGVPQIEVTFEIDVNGILHVSAEDKGTGNKNKLTITNDHNRLSPEDIERMINDADK 549

  Fly   525 YRNEDEKQKETIAAKNGLESYCFNMKATL-DEDNLKTKISDSDRTTILDKCNETIKWLDANQLAD 588
            :..:|:.|||.:.::|.||:|.:.||..: |::.|..|::|.|:.:|.......|:||.:||.|.
 Worm   550 FAADDQAQKEKVESRNELEAYAYQMKTQIADKEKLGGKLTDEDKVSIESAVERAIEWLGSNQDAS 614

  Fly   589 KEEYEHRQKELEGVCNPIITKLYQGAG 615
            .||.:.::||||.|..||::|||...|
 Worm   615 TEENKEQKKELESVVQPIVSKLYSAGG 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	373/607 (61%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	252/375 (67%)
hsp-4	NP_001370395.1	PTZ00009	33..643	CDD:240227	375/612 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.730