Protein Alignment Hsc70-4 and T24H7.2

DIOPT Version :10

• Sequence 1: NP_524356.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_495249.1
• Gene: T24H7.2 / 174033
• WormBaseID: WBGene00020781
• Length: 925
• Species: Caenorhabditis elegans
• Alignment Length: 756
• Identity: 191/756 - (25%)
• Similarity: 315/756 - (41%)
• Gaps: 170/756 - (22%)

  Fly     6 AVGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFD 69
            |:.|||||.:..:|:.:.| .::|..|.:..|.||:.|...|..|...|||.......|
 Worm    26 AMTIDLGTQFLKIGIVKPGIPMDIALNTESRRKTPNVVMIQDGHRTFADAAIGMQVRYP------ 84

  Fly    70 AKRLIGRKFDDAAVQSDMKHWPFEV-------VSADGKPK--IEVTYKDEKKTFFPEEISSMVLT 125
              .|:..:.:| .|....:|..||:       ...|..||  ..:.:|...:::..|.:::|:|.
 Worm    85 --HLVHGQLND-LVGKSTQHPSFELFKRRNTFFEVDDAPKNASSINFKLGGESYTVEALTAMILA 146

  Fly   126 KMKETAEAYL-GKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL-DKK 188
            ..|:..|.|. ...:.:.|||||.||..::|.|.:.|..:|||.||::||:.||||:::|: .:|
 Worm   147 NAKKFTEEYAQAAEIKDVVITVPVYFTPAERLAVERAAQMAGLTVLQLINDGTAAALSHGIFRRK 211

  Fly   189 AVGER--NVLIFDLGGGTFDVSILSI--------DDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQ 243
            .:||:  .::::|:|......:|:..        ......|.....|..|||.:..|||..|.::
 Worm   212 EIGEKPQRLMVYDMGAAKTTATIVEFKLVKEKYEKQPKMTVLGVGFDRTLGGIEMTNRLRDHLIE 276

  Fly   244 EFKR--KHKKDLTTNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELN 306
            .|::  |.|..:.||:||:.:.....||.|:.||::.:...:|:|..|..|....:||..|..|.
 Worm   277 MFEKNYKPKTKVNTNRRAMTKFSKEAERLKQVLSANAEHFAQIESAHEDIDAKLKVTREDFNHLI 341

  Fly   307 ADLFRSTMDPVEKALRDAKLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAY 371
            :|:.....:|:|:|||.|::....|...||:|..||:||||.::|.....||:.|.:|.|||||.
 Worm   342 SDMESRFGEPIEQALRMAQIPIDDIDQFVLMGAGTRVPKVQEIVQKTIGTKEIGKFLNTDEAVAM 406

  Fly   372 GAAVQAAILHGDKSQEVQDLLLLD--VTPLSLGI----------ETAG--GVMSVLIKRNTTIPT 422
            ||..|||  |..|..:|:...:.:  :.|:.:..          |..|  .|:..|...|:..||
 Worm   407 GALFQAA--HLSKGFKVKPFNIEEKVIFPVEVHFVSKIRDEKTEEITGEKNVVKTLFAANSVYPT 469

  Fly   423 -KQTQTFTTYSDNQPGVLIQVYEGERAMTK----------DNNLLGKFELSGIPPAPRG------ 470
             .:|.:.|:|||:....|  .|....:.||          ||  |...|:||:..|.:.
 Worm   470 HPKTISLTSYSDDFSVAL--KYGKIESFTKQQVQEIGSLLDN--LVDVEISGLSEALKNRSSEES 530

  Fly   471 -VPQIEVTFDIDANGILNVTALE------------------------------------------ 492
             ...::|:|.:||:||:.|...|
 Worm   531 EFKGVKVSFIVDASGIVRVRRAEALFEPKSGLVGSIASTISGLFSSKTEEGEPTTDDSTPQSTEE 595

  Fly   493 -----------------------RSTNKENKITITNDKGRLSKEDIE--------------RMVN 520
                                   .||::|:..|...:|...|....|              |:.|
 Worm   596 KTEEKESVKVEDSTPEPEPETPVNSTSEESPKTNETEKNASSGNATEVKEKKKELPSIVRLRITN 660

  Fly   521 E------AEKYRNEDEKQK------------ETIAAKNGLESYCFNMKATLDEDNLKTKISDSDR 567
            :      ..||..::||::            |..|.:|.|||:.|.....|:|......::|.::
 Worm   661 KYPSAFVPNKYDVQEEKRRMEAFAEKERLASERAAVENELESFNFECSQYLEETEFTDYMADEEK 725

  Fly   568 TTILDKCNETIKWLDANQLAD--KEEYEHRQKELEGVCNPI 606
            |.:.|.......||:.:...|  .:::.....||:.|...:
 Worm   726 TKLEDSVKRIRAWLEDDVTKDTPTKDFTDNLLELKNVVRSV 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_524356.1	PTZ00009	1..612	CDD:240227	191/756 (25%)
T24H7.2	NP_495249.1	ASKHA_NBD_HSP70_HYOU1	25..413	CDD:466828	123/395 (31%)