Protein Alignment Hsc70-4 and hsp-70

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_492485.1
• Gene: hsp-70 / 172757
• WormBaseID: WBGene00002026
• Length: 643
• Species: Caenorhabditis elegans
• Alignment Length: 664
• Identity: 431/664 - (64%)
• Similarity: 527/664 - (79%)
• Gaps: 34/664 - (5%)

  Fly     1 MSKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQ 65
            ||...|:||||||||||||::|:|||||:||.:||:||||||||||||||:|||||:|.|.||..
 Worm     1 MSTCKAIGIDLGTTYSCVGIYQNGKVEILANSEGNKTTPSYVAFTDTERLVGDAAKDQAARNPEN 65

  Fly    66 TIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKET 130
            |:|||||||||:||:..||||:|||||.|....|||.:||..|.||:.|..||||:|||.|||||
 Worm    66 TVFDAKRLIGRRFDEETVQSDIKHWPFTVKGKQGKPVVEVEVKGEKREFNAEEISAMVLQKMKET 130

  Fly   131 AEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNV 195
            |||.||.:|.:||||||||||||||||||||.||||||.:||||||||||:||||||....|:|:
 Worm   131 AEAVLGHSVRDAVITVPAYFNDSQRQATKDAATIAGLNAIRIINEPTAAALAYGLDKGITDEKNI 195

  Fly   196 LIFDLGGGTFDVSILSIDDG-IFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRA 259
            |||||||||||||||||.:| |||||||||||||||||||:|::.||:.|||||..||:::|.||
 Worm   196 LIFDLGGGTFDVSILSIAEGSIFEVKSTAGDTHLGGEDFDSRVLQHFMTEFKRKTGKDISSNPRA 260

  Fly   260 LRRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDA 324
            :||||||||||||||||||:|::|:||||:|||||:.|||||||||.|||||.|::|||||||||
 Worm   261 IRRLRTACERAKRTLSSSTEATVEVDSLFDGTDFYSKITRARFEELCADLFRKTLEPVEKALRDA 325

  Fly   325 KLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQ 389
            |.||..|.::|||||||||||:|:||::.||||:||.|||||||||:|||||||:|.|.|...::
 Worm   326 KTDKGRIDEVVLVGGSTRIPKIQKLLKEFFNGKDLNCSINPDEAVAFGAAVQAAVLSGVKDDTIK 390

  Fly   390 DLLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNN 454
            |:||:||.|||.|||||||||:.||.|||.||.|.::|||||:||||||.|||||||||||:||:
 Worm   391 DVLLVDVVPLSHGIETAGGVMTNLIDRNTRIPAKASKTFTTYADNQPGVSIQVYEGERAMTRDNH 455

  Fly   455 LLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMV 519
            .||.|||:|||||||||||::|||||||||||||:|.::||.:.|:|||.|:|||||:.||:|||
 Worm   456 RLGTFELTGIPPAPRGVPQVDVTFDIDANGILNVSAADKSTGRSNRITIRNEKGRLSQADIDRMV 520

  Fly   520 NEAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDAN 584
            |||:::..||..|::.|:::|.||:|.|.:|..|:|........|:.|..  |...:|::|::.|
 Worm   521 NEAKQFEREDAAQRDRISSRNQLEAYAFQVKQALEEHGSLLSAEDAKRAK--DAVEDTLRWMERN 583

  Fly   585 QLADKEEYEHRQKELEGVCNPIITKLYQ-----GAGFPPGGMPGGPGGMPGAAGAAGAAGAGG-- 642
            .||||:|.|.:.|||:.:|..|:||::|     |:|                   .|..|:||
 Worm   584 TLADKDEIEAKDKELKSICQDILTKMHQQEAQSGSG-------------------CGNPGSGGFH 629

  Fly   643 -----AGPTIEEVD 651
                 .|||:||||
 Worm   630 SSNYPQGPTVEEVD 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	417/611 (68%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	282/375 (75%)
hsp-70	NP_492485.1	PTZ00009	1..643	CDD:240227	429/662 (65%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	282/375 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.730