Protein Alignment Hsc70-4 and hspa12a

DIOPT Version :9

• Sequence 1: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: XP_002941887.2
• Gene: hspa12a / 100489323
• XenbaseID: XB-GENE-959285
• Length: 664
• Species: Xenopus tropicalis
• Alignment Length: 671
• Identity: 142/671 - (21%)
• Similarity: 229/671 - (34%)
• Gaps: 240/671 - (35%)

  Fly     7 VGIDLGTTYS-----------CVGVFQHGKVEIIANDQG--NRTTPSYVAFTDTERLIGDAAKNQ 58
            |.||.|||.|           |:.:.:..:    ..|.|  |:.||:      |..|:.|..
 Frog    56 VAIDFGTTSSGYAYSFSKEPECIHIMRRWE----GGDPGVSNQKTPT------TMLLMPDRK--- 107

  Fly    59 VAMNPTQTIFDAKRLIGRKFDDAAVQSDMKHWPF------------------EVVSADGK--PKI 103
                     |.:.....|.|......|:.|||.:                  |:.:|:||  ..:
 Frog   108 ---------FHSFGFAARDFYHDLDPSESKHWLYFEKFKMKLHSSTDLTMETELTAANGKRVKAL 163

  Fly   104 EV-TYKDEKKTFFPEEISSMVLTKMKETAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGL 167
            |: .|..:   :|.|:    .|.::.:.|.:.:.......||||||.:....:|..:.|...||:
 Frog   164 EIFAYALQ---YFKEQ----ALKELSDQAGSEMDSAEVRWVITVPAIWKQPAKQFMRQAAYKAGM 221

  Fly   168 ------NVLRIINEPTAAAI---------AYGLDKKAV--------------------------- 190
                  ..|.|..||..|:|         ...|..||.
 Frog   222 ATPENPEQLIIALEPEGASIYCRKLRLHQMIDLSSKAAINGISPTDPAKDLARRNRQSRTFLVEN 286

  Fly   191 -----------GERNVLIFDLGGGTFDVSI--LSIDDGIFE--VKSTAGDTHLGGEDFD-NRLV- 238
                       |:|.|:: |.||||.|:::  :.:.:|..:  .|::.|.....|.|:: .:|:
 Frog   287 VIGELWSELEEGDRYVVV-DCGGGTVDLTVHQIRLPEGHLKELYKASGGPYGSLGVDYEFEKLLC 350

  Fly   239 ----THFVQEFKRKHKKDLTTNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGTDFY----- 294
                ..|:..||.|       ...|...|..|.|..||..:......:.|...|...|:|
 Frog   351 KIFGDDFIDTFKVK-------RPAAWVDLMIAFESRKRAAAPDRTNPLNITLPFSFIDYYKKFRG 408

  Fly   295 -------------------TSITRARFEELNADLFRSTMDPVEKALRD--AKLDKSVIHDIVLVG 338
                               ..:.|...:.:|| ||:.|:||:.:.|.:  .|.:.:.:..:.|||
 Frog   409 HSVEHALRKSNVDFVKWSSQGMLRMNPDAMNA-LFKPTIDPIIQHLTNLFQKPEVAGVKFLFLVG 472

  Fly   339 GSTRIPKVQRLLQDLFNGKELNKSINPD-----------------------EAVAYGAAVQAAIL 380
            |....|.:|:.:|..| |.:....|..|                       ..:.||..|....:
 Frog   473 GFAESPLLQQAVQQAF-GDQCRVIIPHDVGLTILKGAVLFGLDPALIKVRRSPLTYGVGVLNRYV 536

  Fly   381 HGDKSQEVQDLLLLDVT---------------PLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTT 430
            .|....|  .|||.|.|               .::|| ||        :||:.| |.||:|..
 Frog   537 EGKHPPE--KLLLKDGTRWCTDVFDKFILADQSVALG-ET--------VKRSYT-PAKQSQLI-- 587

  Fly   431 YSDNQPGVLIQVYEGERAMTKDNNLLG----------KFELSGIPPAPRGVP---QIEVTFDIDA 482
                   ::|.:|..|:   .|.|.:.          :.:|:|...||  ||   :|:.......
 Frog   588 -------IIIHIYSSEQ---DDANFITDKGVRKCGTLRLDLTGPESAP--VPSRREIQTIMQFGD 640

  Fly   483 NGILNVTALERSTNKENKITI 503
            ..| ..||::.:|:|..|::|
 Frog   641 TEI-KATAVDVATSKNVKVSI 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	142/671 (21%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	105/519 (20%)
hspa12a	XP_002941887.2	HSPA12A_like_NBD	54..513	CDD:212685	102/495 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910