DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art3 and GSTCD

DIOPT Version :9

Sequence 1:	NP_650434.1	Gene:	Art3 / 41837	FlyBaseID:	FBgn0038306	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001026890.2	Gene:	GSTCD / 79807	HGNCID:	25806	Length:	633	Species:	Homo sapiens

Alignment Length:	194	Identity:	45/194 - (23%)
Similarity:	74/194 - (38%)	Gaps:	67/194 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 EVPANSSSDEDEYDDIDDDDEPMDEGDEL-----TTCL---------FCTETSANISVAIDHLDA 71
            ||..:||...|  |.|.|.:..:....||     ..||         ||   .|.::|.:.|:
Human    55 EVSRDSSLLRD--DLIQDVEIQIISRQELPPIVQNCCLPAVVERSDNFC---RAGLAVVLRHI-- 112

  Fly    72 RHKVNLSQLQRKFEMD--QYSFIKLINYIR-AKKISAE-----QLLSAEHPLWQDEKYLQPGEYE 128
                    :|:.:|.|  :...::|:.:.: ..|..||     :|.....|| ..|.:|:....:
Human   113 --------IQKSYEADPLKKELLELLGFKKTCLKACAEVSQWTRLCELTIPL-AIENFLRESSDQ 168

  Fly   129 PWLCYDYEVLKTDGAPTQP-SVLELQQRIAEQSQLLQQANEDMERMRNDYKALLQKV---HADG 188
            |              ||.| .:|:|:::::|.           .|:.||.|...||:   .|||
Human   169 P--------------PTIPVEILQLEKKLSEP-----------VRVHNDDKLRRQKLKQQKADG 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art3	NP_650434.1	Methyltransf_18	243..346	CDD:289607
GSTCD	NP_001026890.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	191..233		8/17 (47%)
		GST_C_family	<270..329	CDD:351885
		AdoMet_MTases	423..541	CDD:354317
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900