DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art3 and prmt9

DIOPT Version :9

Sequence 1:	NP_650434.1	Gene:	Art3 / 41837	FlyBaseID:	FBgn0038306	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001124239.1	Gene:	prmt9 / 553290	ZFINID:	ZDB-GENE-080728-4	Length:	859	Species:	Danio rerio

Alignment Length:	327	Identity:	77/327 - (23%)
Similarity:	144/327 - (44%)	Gaps:	72/327 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   218 HHEMLSDKVRTSTYRASLLQNEAVVRG-KTVLDVGCGTGILSIFASKAGAARVVGIDNSDIVY-T 280
            |..||:|..|...|:.::  .:||..| .:|||:|.|||||.:.|..||||.|...:.|..:| .
Zfish   156 HFLMLNDHGRNHKYQLAI--KKAVEGGCSSVLDIGTGTGILGMCAKMAGAAEVYACELSKTMYEL 218

  Fly   281 AMDIIRKNKVEN-VELIKGRLEDTDLPE---TKYDIIISEWMGYFLLYESMLDSIIYARENHLNP 341
            |.:::..|.:.: ::::..:..|.::|:   .:..::::|.:...|..|.:::::|:|.::.|.|
Zfish   219 ACEVLSANGMADCIKILHRKSLDMEIPKDIPNRVSLVVTETVDAGLFGEGIIETLIHAWKHLLLP 283

  Fly   342 -------------NGIILPSRCTLSLLGYGDDTLYADEVE-----FWSNVYEVDMSDLRKQSIEE 388
                         .|.::|:..|:    :| ..:...|:.     ..|:|..:|:|.:.:  |..
Zfish   284 PPNPGELLSSPSQTGRVIPAGATV----FG-VAVQCPEIRRHHRLCVSSVGGLDLSAVGQ--IYS 341

  Fly   389 PLMQVVDAE------------------FMLTEPEQIANFDIMTVDMNYPNFTH----------QF 425
            |:..:.|.|                  ..||:|     |..:.:|.|  |...          |.
Zfish   342 PVSCLADTEDSTEPYTTERLSRLRGGYIQLTQP-----FTALDIDFN--NVQELEGLCSREVVQL 399

  Fly   426 SLKVTKPGRLSAFVGYFETLFELPSPVMFSTSPSATPTHWKQTVFFIENP-QVVKEGDVICGKIT 489
            .|.||:.|.|.|...:|:  ..|......||.|. ..|.|:|.::.:::. ..||.||.|..:::
Zfish   400 CLCVTQDGILDALAVWFQ--LHLDQDNHLSTGPQ-EETCWEQAIYPVQSTFNSVKRGDEILVEVS 461

  Fly   490 SR 491
            .:
Zfish   462 CK 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art3	NP_650434.1	Methyltransf_18	243..346	CDD:289607	30/121 (25%)
prmt9	NP_001124239.1	TPR_11	72..135	CDD:290150
		TPR repeat	72..98	CDD:276809
		MAS20	<96..133	CDD:295844
		TPR repeat	103..133	CDD:276809
		AdoMet_MTases	151..>267	CDD:302624	32/112 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810