Protein Alignment Art3 and PRMT6

DIOPT Version :10

• Sequence 1: NP_650434.1
• Gene: Art3 / 41837
• FlyBaseID: FBgn0038306
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_060607.2
• Gene: PRMT6 / 55170
• HGNCID: 18241
• Length: 375
• Species: Homo sapiens
• Alignment Length: 321
• Identity: 114/321 - (35%)
• Similarity: 174/321 - (54%)
• Gaps: 32/321 - (9%)

  Fly   205 DNEYFKSYAHFGIHHEMLSDKVRTSTYRASLLQNEAVVRGKTVLDVGCGTGILSIFASKAGAARV 269
            |..|::.|:...:|.||::|:|||..||..:|:|.|.:|||||||||.||||||||.::|||.||
Human    44 DQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRV 108

  Fly   270 VGIDNSDIVYTAMDIIRKNKVEN-VELIKGRLEDTDLPETKYDIIISEWMGYFLLYESMLDSIIY 333
            ..::.|.|...|.:::|.|.:|: |.::.|.:|..:||| :.|.|:||||||.||:||||.|:::
Human   109 YAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPE-QVDAIVSEWMGYGLLHESMLSSVLH 172

  Fly   334 ARENHLNPNGIILPSRCTLSLLGYGDDTLYADEVEFWSNV---YEVDMSDLR------KQSIEEP 389
            ||...|...|::||:...|.:....|..| ...:.|||.|   |.||||.|.      .....|.
Human   173 ARTKWLKEGGLLLPASAELFIAPISDQML-EWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEI 236

  Fly   390 LMQVVDAEFMLTEPEQIANFDIMTVDMNYPNFTHQFSLKVTKPGR----------LSAFVGYFET 444
            ::|.:..|.:|..|::.|..::....:       :..|:....||          :..|..:|:.
Human   237 VVQGLSGEDVLARPQRFAQLELSRAGL-------EQELEAGVGGRFRCSCYGSAPMHGFAIWFQV 294

  Fly   445 LF---ELPSPVMFSTSPSATPTHWKQTVFFIENPQVVKEGDVICGKITSRRHKEDVRGLSV 502
            .|   |...|::.||||....|||||.:.::..|..|::...:.|:||....:::.|.|.|
Human   295 TFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRV 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Art3	NP_650434.1	COG4076	218..416	CDD:443253	86/207 (42%)
PRMT6	NP_060607.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38
		COG4076	51..>223	CDD:443253	80/173 (46%)