DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art3 and Trmt9b

DIOPT Version :9

Sequence 1:	NP_650434.1	Gene:	Art3 / 41837	FlyBaseID:	FBgn0038306	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001371028.1	Gene:	Trmt9b / 319582	MGIID:	2442328	Length:	447	Species:	Mus musculus

Alignment Length:	314	Identity:	54/314 - (17%)
Similarity:	93/314 - (29%)	Gaps:	133/314 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 LQNEAVVR----------GKTVLDVGCGTG-------------------ILSIFASKAGAARVVG 271
            ||::|..|          |..|.|:|||||                   ::.|..::  ...|:.
Mouse    27 LQSKAWPRVRQFLQDQKPGSLVADIGCGTGKYLKVNSQVHTLGCDYCGPLVEIARNR--GCEVMV 89

  Fly   272 IDNSDIVY--------TAMDIIR--KNKVENVELIK---------GRL-------EDTDLPETKY 310
            .||.::.:        .::.:|.  ..|...:..||         |:|       |..:....|.
Mouse    90 CDNLNLPFRDQGFDAIISIGVIHHFSTKERRIRAIKEMARVLAPGGQLMIYVWAMEQKNRRFEKQ 154

  Fly   311 DIII---------------SEW------------------MGYFLLYESMLDSIIYARENHLNPN 342
            |:::               ..|                  .|..:.::...||    :.:|....
Mouse   155 DVLVPWNRALCSRLLSESHQSWGHHCEHPRSRGFQGPGSVCGCAVCFKGRCDS----KRSHSMDY 215

  Fly   343 GIILPSRC--TLSLLGYGDDTLYAD---EVEFWSNVYEVDMSDLRKQSIEEPLMQVVDAEFMLTE 402
            |..:...|  .:|..|..::.||::   ....|.....:|.|.||||......|::
Mouse   216 GSAVARTCCEAISKEGERENGLYSNFGKSFRSWFFSRSLDESTLRKQIERVRPMKI--------- 271

  Fly   403 PEQIANFDIMTVDMNYPNFTHQFSLKVTKPGRLSAFVGYFETLFELPSPVMFST 456
            ||..||..:......:|:                         .:|.:|..|||
Mouse   272 PEAWANSTVSQQPSRHPS-------------------------LDLHAPEPFST 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art3	NP_650434.1	Methyltransf_18	243..346	CDD:289607	28/190 (15%)
Trmt9b	NP_001371028.1	Methyltransf_25	48..135	CDD:404528	15/88 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	274..306		8/52 (15%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	320..348
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900