Protein Alignment Art3 and CARM1

DIOPT Version :9

• Sequence 1: NP_650434.1
• Gene: Art3 / 41837
• FlyBaseID: FBgn0038306
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_954592.1
• Gene: CARM1 / 10498
• HGNCID: 23393
• Length: 608
• Species: Homo sapiens
• Alignment Length: 414
• Identity: 110/414 - (26%)
• Similarity: 191/414 - (46%)
• Gaps: 84/414 - (20%)

  Fly   120 KYLQPGEYEPWLCYDYEVLKT-DGAPTQPSVLELQQRIAEQSQLLQQANEDMERMRNDYKALLQK 183
            ::..|.::    |..|.:||| .|...:.||  ..:|..|.|.:
Human   110 QFATPNDF----CSFYNILKTCRGHTLERSV--FSERTEESSAV--------------------- 147

  Fly   184 VHADGEPKGSDQSVPRNNVCLDNEYFKSYAHFGIHHEMLSDKVRTSTYRASLLQNEAVVRGKTVL 248
                                   :||:.|.:......|:.|.|||.||:.::|||....:.|.||
Human   148 -----------------------QYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVL 189

  Fly   249 DVGCGTGILSIFASKAGAARVVGIDNSDIVYTAMDIIRKNKV-ENVELIKGRLEDTDLPETKYDI 312
            |||||:||||.||::|||.::..::.|.:...|..:::.|.: :.:.:|.|::|:..||| :.||
Human   190 DVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPE-QVDI 253

  Fly   313 IISEWMGYFLLYESMLDSIIYARENHLNPNGIILPSRCTLSLLGYGDDTLYADE---VEFW--SN 372
            ||||.|||.|..|.||:|.::|:: :|.|:|.:.|:...:.|..:.|:.||.::   ..||  .:
Human   254 IISEPMGYMLFNERMLESYLHAKK-YLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPS 317

  Fly   373 VYEVDMSDLRKQSIEE----PLMQVVDAEFMLTEP-EQIANF------DIMTVDMNYPNFTHQFS 426
            .:.||:|.||..:::|    |::...|...::.:. :...||      |:..:::       .|.
Human   318 FHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEI-------PFK 375

  Fly   427 LKVTKPGRLSAFVGYFETLFELPS--PVMFSTSPSATPTHWKQTVFFIENPQVVKEGDVICGK-- 487
            ..:...|.:.....:|:..| :.|  .|..||:|:...|||.|.....::|...|.||.:.|.
Human   376 FHMLHSGLVHGLAFWFDVAF-IGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCL 439

  Fly   488 -ITSRRHKEDVRGLSVDIEVFGKK 510
             |.::|...|: .:...::..|.|
Human   440 LIANKRQSYDI-SIVAQVDQTGSK 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Art3	NP_650434.1	Methyltransf_18	243..346	CDD:289607	44/103 (43%)
CARM1	NP_954592.1	CARM1	34..138	CDD:288395	9/33 (27%)
		PRMT5	<172..435	CDD:282971	83/272 (31%)
		Methyltransf_18	184..283	CDD:289607	43/100 (43%)
		Transactivation domain. /evidence=ECO:0000250	499..608

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820