Protein Alignment Caf1-55 and HAT2

DIOPT Version :10

• Sequence 1: NP_524354.1
• Gene: Caf1-55 / 41836
• FlyBaseID: FBgn0263979
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_010858.3
• Gene: HAT2 / 856654
• SGDID: S000000782
• Length: 401
• Species: Saccharomyces cerevisiae
• Alignment Length: 405
• Identity: 148/405 - (36%)
• Similarity: 224/405 - (55%)
• Gaps: 41/405 - (10%)

  Fly    21 INEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTKQDGKDYSVHRLILGTHTS-DEQNHLL 84
            ::|||.:||.|.|.:||.|....|.|||||.||||...::....:....||:||||| :|:|:|.
Yeast    10 VDEEYDLWKSNVPLMYDFVSETRLTWPSLTVQWLPTPVQELDGGFIKQELIIGTHTSGEEENYLK 74

  Fly    85 IASVQLP-----SEDAQFD-GSHYDNEKGEFGGFGSVCGKIEIEIKINHEGEVNRARYMPQNACV 143
            .|.:.||     :||.|.: |..|.:      ...:....|.|..|..||.|:.|||||||:..:
Yeast    75 FAEINLPKEILSNEDPQEEAGEEYQS------SLPAPRSNIRITAKYEHEEEITRARYMPQDPNI 133

  Fly   144 IATKTPSSDVLVFDYTKHPSKPEPSGECQPDLRLRGHQKEGYGLSWNPNLNGYLLSASDDHTICL 208
            :||......|.::..::....           .|:.|:..||.||::..:.|.|||.|||||:.|
Yeast   134 VATINGQGTVFLYSRSEGLQS-----------TLKFHKDNGYALSFSTLVKGRLLSGSDDHTVAL 187

  Fly   209 WDINATPKEHRVIDAKNIFTGHTAVVEDVAWHLLHESLFGSVADDQKLMIWDTRNNNTSKPSHTV 273
            |::.:.....:.:...|..  |:.::.|..||..::.|||:|::|..|.|.|.|.|||     |:
Yeast   188 WEVGSGGDPTKPVRTWNDL--HSDIINDNKWHNFNKDLFGTVSEDSLLKINDVRANNT-----TI 245

  Fly   274 DAHTAEVNC------LSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPH 332
            |.    |.|      |:|:.:|..:||....|..|.|:||||:|..||....|:|.:..:::|.|
Yeast   246 DT----VKCPQPFNTLAFSHHSSNLLAAAGMDSYVYLYDLRNMKEPLHHMSGHEDAVNNLEFSTH 306

  Fly   333 NETILASSGTDRRLHVWDLSKIGEEQSTEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWIICSV 397
            .:.::.|||:|.||.:|||.:||.||:.:|||||.|||:.:|.||.:.::||..||..||::.|.
Yeast   307 VDGVVVSSGSDNRLMMWDLKQIGAEQTPDDAEDGVPELIMVHAGHRSSVNDFDLNPQIPWLVASA 371

  Fly   398 SEDNIMQVWQMAENV 412
            .|:||:|||:.:.::
Yeast   372 EEENILQVWKCSHSL 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Caf1-55	NP_524354.1	CAF1C_H4-bd	23..92	CDD:463513	33/74 (45%)
		WD40 repeat	132..179	CDD:293791	11/46 (24%)
		WD40	<176..409	CDD:441893	94/238 (39%)
		WD40 repeat	184..228	CDD:293791	16/43 (37%)
		WD40 repeat	235..274	CDD:293791	16/38 (42%)
		WD40 repeat	280..318	CDD:293791	17/43 (40%)
		WD40 repeat	324..375	CDD:293791	23/50 (46%)
		WD40 repeat	381..406	CDD:293791	11/24 (46%)
HAT2	NP_010858.3	CAF1C_H4-bd	12..82	CDD:463513	32/69 (46%)
		WD40	<117..380	CDD:441893	105/284 (37%)
		WD40 repeat	122..158	CDD:293791	11/46 (24%)
		WD40 repeat	163..204	CDD:293791	15/40 (38%)
		WD40 repeat	212..247	CDD:293791	16/39 (41%)
		WD40 repeat	254..292	CDD:293791	15/37 (41%)
		WD40 repeat	298..349	CDD:293791	23/50 (46%)
		WD40 repeat	355..380	CDD:293791	11/24 (46%)