Protein Alignment Caf1-55 and WTM1

DIOPT Version :10

• Sequence 1: NP_524354.1
• Gene: Caf1-55 / 41836
• FlyBaseID: FBgn0263979
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_014873.3
• Gene: WTM1 / 854405
• SGDID: S000005756
• Length: 437
• Species: Saccharomyces cerevisiae
• Alignment Length: 475
• Identity: 86/475 - (18%)
• Similarity: 174/475 - (36%)
• Gaps: 127/475 - (26%)

  Fly    26 KIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTKQDGKDYSVHRLILGTHTS----DEQNHLLIA 86
            |:||.:||..|:.:       .||..:::..|      |..:|:....|.::    |::|:.|.:
Yeast     4 KVWKSSTPSTYEHI-------SSLRPKFVSRV------DNVLHQRKSLTFSNVVVPDKKNNTLTS 55

  Fly    87 SV-------------QLPSEDAQFDGSHYDNEKGE-FGGFGSVCGKIEIEIKINHEGE-VNRARY 136
            ||             .:|.::|   .|....:.|: |.|..:.    .:..|..::|| |::..|
Yeast    56 SVIYSQGSDIYEIDFAVPLQEA---ASEPVKDYGDAFEGIENT----SLSPKFVYQGETVSKMAY 113

  Fly   137 MPQNA-CVIATKTPSSDVLVF-------------------DYTKHPSKPEPSGECQPDLRLRGHQ 181
            :.:.. ..:.:.:.:..:..|                   .|....|...|....:.|..|   .
Yeast   114 LDKTGETTLLSMSKNGSLAWFKEGIKVPIHIVQELMGPATSYASIHSLTRPGDLPEKDFSL---A 175

  Fly   182 KEGYGLSWNPNLNGYLLSASDDHTICLWDINATPKEH--RVID--------AKNIFTGHTAVVED 236
            ...:|:|            :|..||.....|...::.  ::||        .:.:....|.|...
Yeast   176 ISDFGIS------------NDTETIVKSQSNGDEEDSILKIIDNAGKPGEILRTVHVPGTTVTHT 228

  Fly   237 VAWHLLHESLFGSVADDQKLMIWDTRNNNTSKPSHTV-DAHTAEVNCLSFNPYSEFILATGSADK 300
            |.:...|  :|.|.:||..|..||||.::  ||...: :....::.....:..|..:..||.:..
Yeast   229 VRFFDNH--IFASCSDDNILRFWDTRTSD--KPIWVLGEPKNGKLTSFDCSQVSNNLFVTGFSTG 289

  Fly   301 TVALWDLR-------NLKLKLHS-----------FESHKDEIFQVQWSPHNETILASSGTDRRLH 347
            .:.|||.|       :|..:.:.           :.:..|.:..||:|..:.:...:.|....::
Yeast   290 IIKLWDARAAEAATTDLTYRQNGEDPIQNEIANFYHAGGDSVVDVQFSATSSSEFFTVGGTGNIY 354

  Fly   348 VWD----LSKIGEEQSTEDAEDGPPE-----LLFIHGG-------HTAKISDFSWNPNEPWIICS 396
            .|:    |||...:.:....:|...|     |.|:|.|       ...:.:..:|:|....::.:
Yeast   355 HWNTDYSLSKYNPDDTIAPPQDATEESQTKSLRFLHKGGSRRSPKQIGRRNTAAWHPVIENLVGT 419

  Fly   397 VSEDNIMQVWQMAENVYNDE 416
            |.:|:::.:::    .|.:|
Yeast   420 VDDDSLVSIYK----PYTEE 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Caf1-55	NP_524354.1	CAF1C_H4-bd	23..92	CDD:463513	17/82 (21%)
		WD40 repeat	132..179	CDD:293791	7/66 (11%)
		WD40	<176..409	CDD:441893	51/277 (18%)
		WD40 repeat	184..228	CDD:293791	8/53 (15%)
		WD40 repeat	235..274	CDD:293791	13/39 (33%)
		WD40 repeat	280..318	CDD:293791	8/55 (15%)
		WD40 repeat	324..375	CDD:293791	12/59 (20%)
		WD40 repeat	381..406	CDD:293791	4/24 (17%)
WTM1	NP_014873.3	WD40	<198..304	CDD:441893	24/109 (22%)
		WD40 repeat	225..262	CDD:293791	14/40 (35%)
		WD40 repeat	270..311	CDD:293791	8/40 (20%)
		WD40 repeat	395..429	CDD:293791	4/33 (12%)