DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Caf1-55 and AT2G19540

DIOPT Version :9

Sequence 1:	NP_524354.1	Gene:	Caf1-55 / 41836	FlyBaseID:	FBgn0263979	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_179544.1	Gene:	AT2G19540 / 816473	AraportID:	AT2G19540	Length:	469	Species:	Arabidopsis thaliana

Alignment Length:	469	Identity:	136/469 - (28%)
Similarity:	198/469 - (42%)	Gaps:	113/469 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 EWPSL-TAQWLPDV-TKQDGK----DYSVHRLILGTHTS-----------------DEQNHLL-- 84
            |.||: |..|.|.| |.:||:    |.|.:..:.|.|..                 .|..|.|
plant    23 EIPSIPTRVWQPGVDTLEDGEELQCDPSAYNSLHGFHVGWPCLSFDILGDKLGLNRTEFPHTLYM 87

  Fly    85 IASVQ------------------------LP-----SEDAQFDGSHYDNEKGEFGGFGSVCGKIE 120
            :|..|                        :|     .||...|.....:...:.|...|....|:
plant    88 VAGTQAEKAAHNSIGLFKITNVSGKRRDVVPKTFGNGEDEDEDDEDDSDSDDDDGDEASKTPNIQ 152

  Fly   121 IEIKINHEGEVNRARYMPQNACVIATKTPSSDVLVFDYTKH-----PSKPEPSGECQPDL----- 175
            :. ::.|.|.|||.|.||||:.:..:...|..|.|:|.:.|     .|:.|......|.|
plant   153 VR-RVAHHGCVNRIRAMPQNSHICVSWADSGHVQVWDMSSHLNALAESETEGKDGTSPVLNQAPL 216

  Fly   176 -RLRGHQKEGYGLSWNPNLNGYLLSASDDHTICLWD-------INATPKEHRVIDAKNIFTGHTA 232
             ...||:.|||.:.|:|...|.|||......|.||:       ::..|           |.||||
plant   217 VNFSGHKDEGYAIDWSPATAGRLLSGDCKSMIHLWEPASGSWAVDPIP-----------FAGHTA 270

  Fly   233 VVEDVAWHLLHESLFGSVADDQKLMIWDTRNNNTSKPSHTVDAHTAEVNCLSFNPYSEFILATGS 297
            .|||:.|....|::|.|.:.|..:.:||.|...:  |:.:..||.|:||.:|:|..:..:||:||
plant   271 SVEDLQWSPAEENVFASCSVDGSVAVWDIRLGKS--PALSFKAHNADVNVISWNRLASCMLASGS 333

  Fly   298 ADKTVALWDLRNLK----LKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQ 358
            .|.|.::.|||.:|    :..| ||.||..|..::||.|..:.||.:..|.:|.:||||.  |:.
plant   334 DDGTFSIRDLRLIKGGDAVVAH-FEYHKHPITSIEWSAHEASTLAVTSGDNQLTIWDLSL--EKD 395

  Fly   359 STEDAE-------------DGPPELLFIHGGHTAKISDFSWNPNEPWIICSVSED--NIMQVWQM 408
            ..|:||             |.||:|||:|.|. ..:.:..|:...|.:|.|.:.|  ||:    |
plant   396 EEEEAEFNAQTKELVNTPQDLPPQLLFVHQGQ-KDLKELHWHNQIPGMIISTAGDGFNIL----M 455

  Fly   409 AENVYNDEEPEIPA 422
            ..|:.|....|:||
plant   456 PYNIQNTLPSELPA 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Caf1-55	NP_524354.1	CAF1C_H4-bd	23..92	CDD:403473	20/100 (20%)
		WD40	127..408	CDD:421866	104/317 (33%)
		WD40 repeat	132..179	CDD:293791	16/57 (28%)
		WD40 repeat	184..228	CDD:293791	12/50 (24%)
		WD40 repeat	235..274	CDD:293791	11/38 (29%)
		WD40 repeat	280..318	CDD:293791	15/41 (37%)
		WD40 repeat	324..375	CDD:293791	22/63 (35%)
		WD40 repeat	381..406	CDD:293791	7/26 (27%)
AT2G19540	NP_179544.1	CAF1C_H4-bd	42..108	CDD:289068	10/65 (15%)
		WD40	<157..>392	CDD:225201	84/248 (34%)
		WD40	158..>391	CDD:295369	83/246 (34%)
		WD40 repeat	163..221	CDD:293791	16/57 (28%)
		WD40 repeat	226..264	CDD:293791	11/37 (30%)
		WD40 repeat	273..309	CDD:293791	11/37 (30%)
		WD40 repeat	316..357	CDD:293791	15/41 (37%)
		WD40 repeat	363..390	CDD:293791	9/26 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D831322at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920