DRSC/TRiP Functional Genomics Resources

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Protein Alignment Caf1-55 and DCAF10

DIOPT Version :9

Sequence 1:NP_524354.1 Gene:Caf1-55 / 41836 FlyBaseID:FBgn0263979 Length:430 Species:Drosophila melanogaster
Sequence 2:NP_077321.3 Gene:DCAF10 / 79269 HGNCID:23686 Length:559 Species:Homo sapiens


Alignment Length:262 Identity:66/262 - (25%)
Similarity:102/262 - (38%) Gaps:66/262 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   138 PQNACVIATKTPSSDVLVFDYTKHPSKP--EPSGECQ---------------PDLRLRGHQKE-- 183
            |:::...|...||.          ||.|  .|..:|:               |..||.|..||  
Human    77 PESSTASAPGEPSP----------PSPPCRRPGPDCRAKSRGRHGLGAGLGGPGARLFGWLKERS 131

  Fly   184 -GYGLSWNPNLNGYLLSASDDHTICLWDINATPKEHRVIDAKNIFTGHTAVVEDVAWHLLHESLF 247
             |.||..:|..:.:....|...:|       .|.:...:..:.    |.||..      |..|..
Human   132 LGRGLFVDPARDNFRTMTSLYGSI-------HPADSVYLSTRT----HGAVFN------LEYSPD 179

  Fly   248 GSV----ADDQKLMIWDTRNNNTSKPSHTV-DAHTAEVNCLSFNPYSEFILATGSADKTVALWDL 307
            |||    .:..:::::|.   .:||...|: :||...||.:.|  ....:.||.|.|.|:|||||
Human   180 GSVLTVACEQTEVLLFDP---ISSKHIKTLSEAHEDCVNNIRF--LDNRLFATCSDDTTIALWDL 239

  Fly   308 RNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSTEDAEDGPPELLF 372
            |.|..|:.:...|...:..:::.. |..:|.:||.|..:.:||.::.        .|||.|...|
Human   240 RKLNTKVCTLHGHTSWVKNIEYDT-NTRLLVTSGFDGNVIIWDTNRY--------TEDGCPHKKF 295

  Fly   373 IH 374
            .|
Human   296 FH 297

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Caf1-55NP_524354.1 CAF1C_H4-bd 23..92 CDD:403473
WD40 127..408 CDD:421866 66/262 (25%)
WD40 repeat 132..179 CDD:293791 12/57 (21%)
WD40 repeat 184..228 CDD:293791 7/43 (16%)
WD40 repeat 235..274 CDD:293791 9/43 (21%)
WD40 repeat 280..318 CDD:293791 16/37 (43%)
WD40 repeat 324..375 CDD:293791 13/51 (25%)
WD40 repeat 381..406 CDD:293791
DCAF10NP_077321.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..119 9/51 (18%)
WD40 <164..319 CDD:295369 44/158 (28%)
WD 1 166..205 11/51 (22%)
WD40 <171..>334 CDD:225201 42/147 (29%)
WD40 repeat 172..207 CDD:293791 9/43 (21%)
WD 2 209..247 18/39 (46%)
WD40 repeat 214..250 CDD:293791 16/37 (43%)
WD 3 251..290 10/47 (21%)
WD40 repeat 256..282 CDD:293791 6/26 (23%)
WD 4 296..335 1/2 (50%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 350..396
WD 5 408..448
WD 6 470..508
WD40 517..555 CDD:197651
WD 7 526..559
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0264
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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