DRSC/TRiP Functional Genomics Resources

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Protein Alignment Caf1-55 and Wdr73

DIOPT Version :9

Sequence 1:NP_524354.1 Gene:Caf1-55 / 41836 FlyBaseID:FBgn0263979 Length:430 Species:Drosophila melanogaster
Sequence 2:NP_001100995.1 Gene:Wdr73 / 308751 RGDID:1306429 Length:371 Species:Rattus norvegicus


Alignment Length:385 Identity:87/385 - (22%)
Similarity:146/385 - (37%) Gaps:83/385 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    84 LIASVQLPSEDAQFDGS------HYDNEKGEF-GGFGSVCGKIEI-------------------- 121
            |:.|::|..:...||.|      .:..|||.| .|:.|: .|.||                    
  Rat     8 LVESLRLYQDFHAFDLSGATRVLEWVGEKGVFVAGYESL-KKNEILHLILPLRLSVKENQGLYPE 71

  Fly   122 -EIKINHEGEVNRA----RYMPQNACVIATKTPSSDVLVFDYTKHPSKPEPSGECQPDLRLRGHQ 181
             :.|:.|.|..:||    :::|....::.:..|...:.|:...      |.:...:....:....
  Rat    72 RDFKVRHGGFSDRAVFDLKHVPDTRLLVTSGLPGCYIQVWQIR------EDNDVIEAVSTIDVQD 130

  Fly   182 KEGYGLSWNPNLNGYLLSASDD-HTICLWDINATPKEHRVIDAKNIFTGHTAVVEDV-AWHLLHE 244
            ||.   |..|.::.:..:|... |...|..:.....|.|    |..::..|...|.: :..:|..
  Rat   131 KEE---SLWPRVSIFCSAAPGILHGARLSGLRTVDVESR----KITYSSDTTDSESLSSLQVLDA 188

  Fly   245 SLFGSVADDQKLMIWDTRNNNTSKPSHTVDAHT--------AEVNCLSFNPYSEFILATGSADKT 301
            ..|.......:|.:.|||..  ..|..||....        |||......| ...|.:.|| |..
  Rat   189 DTFAFCGTSGRLGLVDTRQK--WAPLETVSPRAGSSGERWCAEVRSKGQGP-GPCIASLGS-DGQ 249

  Fly   302 VALWDLRNLKLKLHS-----FESHKD-EIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQST 360
            :.|.|.|||:..:.|     |:|..| |:.:|.|:|..:..||.||.|..:.::|:       ::
  Rat   250 LCLLDPRNLRDPVSSAQCPVFKSSPDPELLRVTWAPGLDNCLAISGFDGTVQIYDV-------TS 307

  Fly   361 EDAEDGPPELLFIHGGH----------TAKISDFSWNPNEPWIICSVSEDNIMQVWQMAE 410
            .|.:....|.||||.||          ...::..:|:|::|..:.|.:.|..:.||...:
  Rat   308 WDGKKTQVEALFIHKGHIFLDGNEVESAPLVTTHTWHPSKPRTLLSAASDAALHVWDWVD 367

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Caf1-55NP_524354.1 CAF1C_H4-bd 23..92 CDD:403473 3/7 (43%)
WD40 127..408 CDD:421866 71/310 (23%)
WD40 repeat 132..179 CDD:293791 6/50 (12%)
WD40 repeat 184..228 CDD:293791 8/44 (18%)
WD40 repeat 235..274 CDD:293791 9/39 (23%)
WD40 repeat 280..318 CDD:293791 12/42 (29%)
WD40 repeat 324..375 CDD:293791 14/50 (28%)
WD40 repeat 381..406 CDD:293791 5/24 (21%)
Wdr73NP_001100995.1 WD40 43..>364 CDD:225201 75/345 (22%)
WD40 repeat 86..116 CDD:293791 3/35 (9%)
WD40 repeat 124..173 CDD:293791 10/55 (18%)
WD40 repeat 180..216 CDD:293791 8/37 (22%)
WD40 repeat 279..325 CDD:293791 16/52 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0264
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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