DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12241 and Sgsm2

DIOPT Version :9

Sequence 1:	NP_650432.1	Gene:	CG12241 / 41834	FlyBaseID:	FBgn0038304	Length:	804	Species:	Drosophila melanogaster
Sequence 2:	NP_001361617.1	Gene:	Sgsm2 / 97761	MGIID:	2144695	Length:	1050	Species:	Mus musculus

Alignment Length:	243	Identity:	46/243 - (18%)
Similarity:	98/243 - (40%)	Gaps:	54/243 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   208 QIEKDLLRILPTNACFSNPNGTGIPRLRRILRGIAWLFPDIGYCQGTGVIVACLLLFMEEEN-AF 271
            :|:||:.|.......|:..|   :.|||.|:....|...|:||.||...::|.||:.::.:. |:
Mouse   840 RIDKDVQRCDRNYWYFTTSN---LERLRDIMCSYVWEHLDMGYVQGMCDLLAPLLVILDNDQLAY 901

  Fly   272 WMMATIVEDL---LPA-----SYYSSTLLGIQADQRVMHTLIANYLSSVDESLRKH-DIELSLIT 327
            ...:.:::.:   .|:     |::::           |.:||....|.:.|.:.:: |.......
Mouse   902 SCFSHLMKRMGQNFPSGGAMDSHFAN-----------MRSLIQILDSELFELMHQNGDYTHFYFC 955

  Fly   328 LHWFLTLFANVVHMKILVRIWDWFFYEGSI-----VLFQLTLGMLKVKEQDLKHLENSAQIFNSL 387
            ..|||..|...:..:.:..:|:..:....|     ||| :.|.:::...:.::.        |::
Mouse   956 YRWFLLDFKRELLYEDVFAVWEVIWAARRISSEHFVLF-IALALVEAYREIIRD--------NNM 1011

  Fly   388 SDIPGEVTDVEVLFRQALEVGGSLSQTVIDTHRRRHLAYLMADQGHQI 435
                 :.||:...|.:..|           .|..:.:..:..|..|::
Mouse  1012 -----DFTDIIKFFNERAE-----------RHDAQEILRIARDLVHKV 1043

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	38/181 (21%)
		SH3_SGSM3	540..592	CDD:212747
		RUN	619..773	CDD:280855
Sgsm2	NP_001361617.1	RUN	42..185	CDD:367169
		PH_RUTBC	256..424	CDD:275431
		TBC	<838..1006	CDD:214540	38/180 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900