Protein Alignment CG12241 and GYP5

DIOPT Version :9

• Sequence 1: NP_650432.1
• Gene: CG12241 / 41834
• FlyBaseID: FBgn0038304
• Length: 804
• Species: Drosophila melanogaster
• Sequence 2: NP_015075.1
• Gene: GYP5 / 855827
• SGDID: S000006170
• Length: 894
• Species: Saccharomyces cerevisiae
• Alignment Length: 663
• Identity: 136/663 - (20%)
• Similarity: 246/663 - (37%)
• Gaps: 175/663 - (26%)

  Fly    37 LPPMMEELSVADGLRPNPGGPFS----------ALTASMWPQEILAKLGGGAE---LASGPNDQP 88
            :||.:||...::..|.|    |.          .||.|.     .|:|...||   :||
Yeast   315 VPPPLEEEMKSEKFRKN----FEETKRNSYHHVPLTGSK-----TAQLESTAEINLIAS------ 364

  Fly    89 EYRFDEFGFRVEEEDGPE-----QSSNKLLSIPFVEDAQQRLQWIAHLEFSHNKEAAELSW---- 144
            .||........|.|:..|     ||..|.....|:|:..:..: :.::. ..::|..::.|
Yeast   365 RYRKTSHHLNKEGEETRESLQEGQSFLKSTFTSFLENLSEYNE-VENVN-EEDREMFKIDWSFWT 427

  Fly   145 ----EHVDVMLPRTEKLRNMVRQGIPHTLRAQMWMRLSGALAKKQKSETSYHDIVKASSNDQLMT 205
                ::..|.....|.|...|..|||..:|..:|..::.:.:::.:      ||.:...:.:.:.
Yeast   428 QVVNDYATVASNEPENLEAHVTNGIPPQIRGIIWQLMANSKSREME------DIYETLLDTECLH 486

  Fly   206 SKQIEKDLLRILPTNACFSNPNGTGIPRLRRILRGIAWLFPDIGYCQGTGVIVACLLLFMEEE-N 269
            ...|.:||.|   |.....:.    :..|.::::..:...||:||.||.|.|.|.||:..|.| .
Yeast   487 EATIRRDLRR---TKFVAEDK----MESLYKVIKVYSVYDPDVGYTQGMGFIAAPLLINCENEAE 544

  Fly   270 AFWMMATIVEDLLPASYYSSTLLGIQADQRVMHTLIANYLSSVDESLRKHDIELSLITLHWFLTL 334
            :|.::..::::......:...:.|:.........|:..:..|:...|.:..|..::....||||.
Yeast   545 SFGLLVGLMKNYGLRELFLPGMPGLMLMLYQFDRLLEEHSPSLYNRLIREGISSTMYATQWFLTF 609

  Fly   335 FANVVHMKILVRIWDWFFYEGSIVLFQLTLGMLKVKEQDLKHLENSAQIFNSLSDIPGEVTDVEV 399
            ||....::.::||:|..|.||..||.:..:.::...|:.|..|.     |:.|.|..     .:.
Yeast   610 FAYKFPLEFVLRIFDIVFVEGIEVLLKFAVNLMLKNEETLVKLR-----FDELLDFL-----KDE 664

  Fly   400 LFRQALEVGGSLSQTVIDTHRRRHLAYLMADQGHQIGNPEAAPNLPKQQLARRQVRKSKSILEAF 464
            ||..                      |||       ||.:.|                 |:::..
Yeast   665 LFNY----------------------YLM-------GNQDDA-----------------SVVQMG 683

  Fly   465 LFRGDGNEG--DQLKNKNIRQTEILVDL--REAILKVGRHFITIEPKLAGHIQLTANYSTESHAK 525
            |..|:..:|  |...:.|       |||  .:|:..|....:|:......::::   :..|...:
Yeast   684 LSNGNSFKGNDDGTFSYN-------VDLFVHDAMTGVYITPLTLRRYRGEYVEI---HEKEQKKE 738

  Fly   526 DHENFINVARTR-KRRAKAL-HDFERHDDDELGFRRNDIITIISQKDEHCWVGELNGLRGWFPAK 588
            ||...:.:...: :|.|:.| ||:...:.:.:. ..|::|.           ..||
Yeast   739 DHYESLRIQNHQLQREAQKLEHDYSILNKENIS-AANELIQ-----------NRLN--------- 782

  Fly   589 FVELLDERSKLYTSAGDDAISETVTDLVRGTLAPAIKAFLEHGMKRPTFLGGPIHPWLYIEEAAT 653
            ...||||::.|.         .|:||         ||:.:|..:::...   | :|...:.:|..
Yeast   783 MEMLLDEKNDLI---------NTITD---------IKSQIEEEIRKQNL---P-NPDASLPKADL 825

  Fly   654 REVEKDFESVYSR 666
            ||   |.|...||
Yeast   826 RE---DLERTISR 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	48/214 (22%)
		SH3_SGSM3	540..592	CDD:212747	8/52 (15%)
		RUN	619..773	CDD:280855	12/48 (25%)
GYP5	NP_015075.1	COG5210	154..737	CDD:227535	105/517 (20%)
		SMC_prok_B	726..>891	CDD:274008	32/159 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810