Protein Alignment CG12241 and GYL1

DIOPT Version :10

• Sequence 1: NP_650432.1
• Gene: CG12241 / 41834
• FlyBaseID: FBgn0038304
• Length: 804
• Species: Drosophila melanogaster
• Sequence 2: NP_013917.1
• Gene: GYL1 / 855230
• SGDID: S000004804
• Length: 720
• Species: Saccharomyces cerevisiae
• Alignment Length: 539
• Identity: 103/539 - (19%)
• Similarity: 194/539 - (35%)
• Gaps: 165/539 - (30%)

  Fly   132 EFSHNKEAAELS--W-----EHVDVMLPRTEKLRNMVRQGIPHTLRAQMWMRLSGALAKKQKSET 189
            :.::|:...|:|  |     ::.::::...|.|...:.:|||...|..:|..:|.|.:|
Yeast   258 KINNNEIPEEVSSFWLKVIGDYQNILINDIETLHFQLSRGIPAAYRLVVWQLVSYAKSK------ 316

  Fly   190 SYHDIVKASSNDQLMTSKQIEKDLLRIL---PTNACFSNPNGTGIPRLRRILRGIAWLFPDIGYC 251
            |:..|.:....:......|..::.|:::   |:..         :.|:..:|:......|:..:.
Yeast   317 SFDPIYETYLTEMAPFDVQEFENQLKMMDEVPSEY---------VKRISNVLKAYLLFDPECEFS 372

  Fly   252 QGTGVIVACLLLFMEEE-NAFWMMATIVEDLLPASYYSSTLLGIQADQRV------MHTLIANYL 309
            .....|:..:|...||| |||.::..:::      .|...||.:.:...:      ...|:..:.
Yeast   373 TDIAYIINMILDVCEEEANAFGLLVRLMK------VYGLRLLFLPSASEIDILCYKFDRLVEEFY 431

  Fly   310 SSVDESLRKHDIELSLITLHWFLTLFANVVHMKILVRIWDWFFYEG--SIVLFQLTLGMLKVKEQ 372
            ..:...:.:..:..|:....:|.|||...:..:|..||.|..|.||  ||:....||
Yeast   432 PEIHNHMVEKGVRSSMFLPGFFTTLFQKKLPTEIQPRIGDMVFLEGIDSIMRILATL-------- 488

  Fly   373 DLKHLENSAQIFNSLSDIPGEVTDVEVLFRQALEVGGSLSQTVIDTHRRRHLAYLMADQGHQIGN 437
                |.||                                        |.||..:..|.
Yeast   489 ----LSNS----------------------------------------RDHLLKMGFDD------ 503

  Fly   438 PEAAPNLPKQQLARRQVRKSKSILEAFLFRGDGNEGDQLKNKNIRQTEILVD--LREAILKVGRH 500
                         ..::.|| .:|:|::.:.||..||.|.:..      .:|  |:::::||
Yeast   504 -------------MLELLKS-GLLDAYIKQNDGTRGDTLLSNE------CMDKLLQDSMMKV--- 545

  Fly   501 FITIEPKLAGHIQLTANYST---ESHAKDHENFINVARTRKRRAKALHDFERH----DDDELGFR 558
              .|.||      ....||:   |.|..|:|..:   :.:....|.|| .::|    ::|.....
Yeast   546 --AITPK------TMKKYSSEYEEIHRLDNEKEV---QYKSITEKNLH-LQKHVRKLENDYTSLN 598

  Fly   559 RNDIITIISQKDEH-----CWVGELNGLRGWFPAKFVELLDERSKLYTSAGDDAISETVTDLVRG 618
            | :.:||.::..::     ..:.|.||.:       :::||.:.||.:.....         |.|
Yeast   599 R-EHVTIANELVKNRLNIESVLNENNGYK-------LQILDLKKKLDSEKKKQ---------VLG 646

  Fly   619 TLAP-AIKAFLEHGMKRPT 636
            ...| .:|..||..||:.|
Yeast   647 VYVPNDLKKDLEETMKKNT 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	44/225 (20%)
		SH3_SGSM3	540..592	CDD:212747	11/60 (18%)
		RUN_SGSM3	570..783	CDD:439050	16/73 (22%)
GYL1	NP_013917.1	COG5210	27..569	CDD:227535	78/420 (19%)