DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12241 and AT3G55020

DIOPT Version :9

Sequence 1:	NP_650432.1	Gene:	CG12241 / 41834	FlyBaseID:	FBgn0038304	Length:	804	Species:	Drosophila melanogaster
Sequence 2:	NP_001319752.1	Gene:	AT3G55020 / 824668	AraportID:	AT3G55020	Length:	819	Species:	Arabidopsis thaliana

Alignment Length:	823	Identity:	166/823 - (20%)
Similarity:	309/823 - (37%)	Gaps:	206/823 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DHEGYVGREEHTRKLQNLGSEDDLGELPPMMEELSVADGLRPNPGGPFSALTASMWPQEILAKLG 75
            :.||:...|::..::| |.:     |:.|.:..:.....:|....|..|. :....|:..::...
plant   122 EEEGHPDAEKNVHRVQ-LWT-----EIRPSLRSIEDLMSIRVKKKGDLSK-SEQEAPKVKISPSF 179

  Fly    76 GGAELASGPNDQPEYRFDEFGFRVEE---EDGPEQSSNKLLSIPFVEDAQQRLQWIAHLEFSHNK 137
            ..|:.:.|.:|....  ||| :.||.   :||.......:..||...|
plant   180 DDAKSSKGASDIDSE--DEF-YDVERSDVQDGSSSDGTGVSGIPVAAD----------------- 224

  Fly   138 EAAELSWEHVDVMLPRTEKLRNMVRQGIPHTLRAQMWMRLSGALAKKQKSETSYHDIV------- 195
             |:.||      ..|..|:|..::|.|:|..||.::|....|  .:|::.:..|.:::
plant   225 -ASPLS------TCPWKEELEVLIRGGVPMALRGELWQAFVG--VRKRRCKDYYQNLLAADGSVN 280

  Fly   196 ------------KASSNDQLMTSK----QIEKDLLRILPTNACFSNPNGTGIPRLRRILRGIAWL 244
                        |.||.:.:...:    ||||||.|..|.:....:   .|...|||:|...|..
plant   281 TIEQEDMQHVDDKGSSTESIAVVEKWKGQIEKDLPRTFPGHPALDD---DGRNALRRLLTAYARH 342

  Fly   245 FPDIGYCQGTGVIVACLLLFMEEENAFWMMATIVEDLLPASYYSSTLLGIQADQRVMHTLIANYL 309
            .|.:||||......|.|||.|.||||||.:..:::|.. ..|||..::..|.||.|:..|:....
plant   343 NPSVGYCQAMNFFAALLLLLMPEENAFWALIGLIDDYF-NGYYSEEMIESQVDQLVLEELVRERF 406

  Fly   310 SSVDESLRKHDIELSLITLHWFLTLFANVVHMKILVRIWDWFFYEGS-IVLFQLTLGMLKVKEQD 373
            ..:...|....::::.:|..|||::|.|::..:.::|:||...:||: ::||:..|.::::....
plant   407 PKLVHHLDYLGVQVAWVTGPWFLSIFMNMLPWESVLRVWDVLLFEGTRVMLFRTALALMELYGPA 471

  Fly   374 LKHLENSAQIFNSLSDIPGEVTDVEVLFRQALEVGGSLSQTVIDTHRRRHLAYLMADQGHQIGNP 438
            |...:::......|..:.|...|              .||.|           |.|..|:|
plant   472 LVTTKDAGDAVTLLQSLTGSTFD--------------SSQLV-----------LTACMGYQ---- 507

  Fly   439 EAAPNLPKQQLARRQVRKSKSILEAFLFRGDG------NEGDQLKNKNIRQ--TEILVDLREAIL 495
                |:.:.:|...:.:...:::.|...|..|      ::|...|..|.:|  ..:||| .:|.|
plant   508 ----NVHEIRLQELRSKHRPAVIAALEERSKGLQAWRDSKGLASKLYNFKQDPKSVLVD-SKASL 567

  Fly   496 KVGRHFITIEPKLAGHIQLTANYSTESHAKDHENFINVARTRKRRAKALHDFERHDDDELGFRRN 560
            ..|              .|:.:.|..|:|                                   :
plant   568 SNG--------------SLSRSESGSSNA-----------------------------------D 583

  Fly   561 DIITIISQKDEHCWVGELNGLRGWFPAKFVELLDERSKLYTSAG--DDAISETVTDLVRGTLAPA 623
            :::..::...|...|.:|.....|..|:..:||:|:......|.  :.|:.|.|.:..|..|:..
plant   584 EVLVSLTGDGEVDSVQDLQAQVLWLKAELCKLLEEKRSALLRAEELEIALMEIVKEDNRRQLSAK 648

  Fly   624 IKAFLEHGMKRPTFLGGPIHPWLYIEEAATREVEKDFESVYSRLVLCKTYRLDEDGKVLTPE--E 686
            ::. ||..|..             ::...:.:.|::...:...:.:.:..::.||.::...:  |
plant   649 VEQ-LEQEMAE-------------VQRLLSDKQEQEGAMLQVLMRVEQEQKVTEDARIFAEQDAE 699

  Fly   687 LLYRCVQAINQTHDDAHAQM-DVKLRSLICLGLNEQVLHLWLEVLCACQEVVQKWYHSWSFIDSP 750
            ......|.:.:.:::|.|.: :::.|:::...:.|..|.                |.|......|
plant   700 AQRYAAQVLQEKYEEAVAALAEMEKRAVMAESMLEATLQ----------------YQSGQLKAQP 748

  Fly   751 GWVQIKCELRILSQFAFNLNPDWELPPKR-GKESQPLKDGVRD 792
            ...|:            |.:...|.||.| ...::|...|.||
plant   749 SPRQV------------NQDSSPEPPPSRISLLARPFGLGWRD 779

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	66/237 (28%)
		SH3_SGSM3	540..592	CDD:212747	5/51 (10%)
		RUN	619..773	CDD:280855	19/156 (12%)
AT3G55020	NP_001319752.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1162786at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR22957
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920