DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12241 and sgsm2

DIOPT Version :9

Sequence 1:	NP_650432.1	Gene:	CG12241 / 41834	FlyBaseID:	FBgn0038304	Length:	804	Species:	Drosophila melanogaster
Sequence 2:	XP_003200084.2	Gene:	sgsm2 / 799094	ZFINID:	ZDB-GENE-131119-52	Length:	1056	Species:	Danio rerio

Alignment Length:	233	Identity:	52/233 - (22%)
Similarity:	95/233 - (40%)	Gaps:	47/233 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   208 QIEKDLLRILPTNACFSNPNGTGIPRLRRILRGIAWLFPDIGYCQGTGVIVACLLLFMEEE---- 268
            :|:||:.|.......|::.|   :.:||.|:....|...:|||.||...::|.|::.:::|
Zfish   846 RIDKDVQRCDRNYYYFTSSN---LEKLRNIMCSYVWEHLEIGYVQGMCDLLAPLMVILDDECLAY 907

  Fly   269 NAFWMMATIVEDLLPASYYSSTLLGIQADQRVMHTLIANYLSSV---DESL-----RKHDIELSL 325
            :.|..:...:....|..             ..|.|..||..|.:   |..|     :..|.....
Zfish   908 SCFTQLMRRMSQNFPTG-------------GAMDTHFANMRSLIQILDSELFELMHQNGDYTHFY 959

  Fly   326 ITLHWFLTLFANVVHMKILVRIWDWFFYEGSI-----VLFQLTLGMLKVKEQDLKHLENS----- 380
            ....|||..|...:..:.:..:|:..:....|     ||| :.|.:::|....:  |:|:
Zfish   960 FCYRWFLLDFKRELLYEDVFAVWEVIWVAPRISSKHFVLF-IALALVEVYRDII--LDNNMDFTD 1021

  Fly   381 -AQIFNSLSDIPGEVTDVEVLFRQALEVGGSLSQTVID 417
             .:.||.::    |..||:.:.|.|.|:...: ||:|:
Zfish  1022 IIKFFNEMA----ERHDVQHILRMARELVHKV-QTLIE 1054

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	39/183 (21%)
		SH3_SGSM3	540..592	CDD:212747
		RUN	619..773	CDD:280855
sgsm2	XP_003200084.2	RUN	43..189	CDD:308412
		PH_RUTBC	262..432	CDD:275431
		TBC	<844..1013	CDD:214540	39/185 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900