DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12241 and tbc1d30

DIOPT Version :9

Sequence 1:	NP_650432.1	Gene:	CG12241 / 41834	FlyBaseID:	FBgn0038304	Length:	804	Species:	Drosophila melanogaster
Sequence 2:	XP_017947631.1	Gene:	tbc1d30 / 734068	XenbaseID:	XB-GENE-5823666	Length:	942	Species:	Xenopus tropicalis

Alignment Length:	356	Identity:	81/356 - (22%)
Similarity:	157/356 - (44%)	Gaps:	66/356 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 GIPHTLRAQMWMRL------SGALAKKQKSETSYHDIVKASSNDQLMTSKQIEKDLLRILPTNAC 222
            |||...|.::|:.|      |.::...:....:::|  :::.:|..| ..||.|||.|...::.|
Frog   258 GIPKEWRKRVWLTLADHYLHSISIDWDKTMRFTFND--RSNPDDDSM-GIQIVKDLHRTGCSSYC 319

  Fly   223 FSNPNGTGIPRLRRILRGIAWLFPDIGYCQGTGVIVACLLLFME--EENAFWMMATIVEDLLPAS 285
            ........:. |:|:|...|.....||||||..::.|.:|..||  |.:|..:|..:::.:||.|
Frog   320 GQEAEQDRVV-LKRVLLAYARWNKTIGYCQGFNILAALILEVMEGNEGDALKVMIYLIDKVLPDS 383

  Fly   286 YYSSTLLGIQADQRVMHTLIANYLSSVDESL----RKHDIE---------LSLITLHWFLTLFAN 337
            |:::.|..:..|..|...|:...|..:.:.|    |..:.|         .::.|:.|||||||.
Frog   384 YFANNLRALSVDMAVFRDLVRMKLPELSQHLDVLQRTANKESGGGYEPPLTNVFTMQWFLTLFAT 448

  Fly   338 VVHMKILVRIWDWFFYEGSIVLFQLTLGMLKVKEQDLKHLENSAQIFNSLSDIPGEVTDVEVLFR 402
            .:....:::|||..|:|||.:|.:::|.:.....:.::..:||...::::..:..|:
Frog   449 CLPNHTVLKIWDSVFFEGSEILLRVSLAIWAKLGEQIECCQNSDDFYSTMGRLTQEM-------- 505

  Fly   403 QALEVGGSLSQTVIDTHRRRHLAYLMADQGHQIGNPEAAPNLPKQQLARRQVRKSKSI------L 461
                    |..::||::......|.||             ..|..|||..:.:.:.:|      :
Frog   506 --------LEDSLIDSNELMQTVYSMA-------------QFPFPQLAELREKYTYNITPFPAPV 549

  Fly   462 EAFLFRG------DGNEGDQLKNKNIRQTEI 486
            ::..|.|      |.:|.:::...::....:
Frog   550 KSASFSGRTSKMRDSDEENEIDEDDVNANAV 580

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	63/231 (27%)
		SH3_SGSM3	540..592	CDD:212747
		RUN	619..773	CDD:280855
tbc1d30	XP_017947631.1	TBC	258..477	CDD:214540	63/222 (28%)
tbc1d30	XP_017947631.1	DUF4682	646..789	CDD:374060
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1162786at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920