DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12241 and Grtp1

DIOPT Version :9

Sequence 1:	NP_650432.1	Gene:	CG12241 / 41834	FlyBaseID:	FBgn0038304	Length:	804	Species:	Drosophila melanogaster
Sequence 2:	NP_001355787.1	Gene:	Grtp1 / 66790	MGIID:	1914040	Length:	359	Species:	Mus musculus

Alignment Length:	363	Identity:	99/363 - (27%)
Similarity:	170/363 - (46%)	Gaps:	45/363 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 RFDEFGFRVEEEDGPEQSSNKLLSIPFVEDAQQRLQWIAHLEFSHNKEAAELSWEHVDVMLPRTE 155
            |.|.:||. ..||....:..:..|...|...::.::|...|:.:..              :.::.
Mouse    16 RIDPYGFE-RPEDFDYAAYEEFFSTYLVILTKRAIKWSKLLKGNGG--------------VRKSV 65

  Fly   156 KLRNMVRQGIPHTLRAQMWMRLSGALAKKQKSETSYHDIVKASSNDQLMTSKQIEKDLLRILPTN 220
            .::..||:|||...||::||.:|||.|:..:|...||.:::..|:..|  .:.|..||.|..|.|
Mouse    66 TVKRYVRKGIPLEHRARVWMAVSGAQARMDQSPGYYHRLLEGESSSSL--DEAIRTDLNRTFPDN 128

  Fly   221 ACFSNPNGTGIPRLRRILRGIAWLF----PDIGYCQ-----------------GTGVIVACLLLF 264
            ..|..   |..|.|::.|..:...:    ||:||||                 |...|...|:|.
Mouse   129 VMFRK---TADPCLQKTLYNVLLAYGLHNPDVGYCQCCAQKPGSSAGLRSSLTGMNFIAGYLILI 190

  Fly   265 ME-EENAFWMMATIVEDLLPASYYSSTLLGIQADQRVMHTLIANYLSSVDESLRKHDIELSLITL 328
            .: ||.:||::..:|..:|| .|||..:||::.||.|:..|:...|.:|...:..|.:..:|:..
Mouse   191 TKNEEESFWLLDALVGRILP-DYYSPAMLGLKTDQEVLAELVRMKLPAVAALMDGHGVLWTLLVS 254

  Fly   329 HWFLTLFANVVHMKILVRIWDWFFYEGSIVLFQLTLGMLKVKEQDLKHLENSAQIFNSLSDI-PG 392
            .||:.||.:::.::.::||||..|.|||.::|::.|.::|..::.:....:...|.:....| .|
Mouse   255 RWFICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLIKQHQEFILEASSIPDICDKFKQITKG 319

  Fly   393 E-VTDVEVLFRQALEVGGSLSQTVIDTHRRRHLAYLMA 429
            : ||:.....::.....||||.|.|...|:...|.|.|
Mouse   320 DFVTECHAFMQKIFSEPGSLSMTTITRLRKSCRAALQA 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	74/235 (31%)
		SH3_SGSM3	540..592	CDD:212747
		RUN	619..773	CDD:280855
Grtp1	NP_001355787.1	TBC	71..301	CDD:214540	74/235 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1162786at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R540
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850