DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12241 and usp6nl

DIOPT Version :9

Sequence 1:	NP_650432.1	Gene:	CG12241 / 41834	FlyBaseID:	FBgn0038304	Length:	804	Species:	Drosophila melanogaster
Sequence 2:	XP_005164934.1	Gene:	usp6nl / 561983	ZFINID:	ZDB-GENE-041210-192	Length:	849	Species:	Danio rerio

Alignment Length:	363	Identity:	86/363 - (23%)
Similarity:	148/363 - (40%)	Gaps:	72/363 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 EILAKLGGGAELAS-GPNDQPEYRF----DEFGFRVEEEDGPEQSSNKLLSIPFVEDAQQRLQ-- 126
            |||||...|.|.|. .|.::..:..    |.|||..|.|          |....||:.|::|:
Zfish    41 EILAKYDKGKEKAEVEPWEETNFELYKAVDRFGFLHEGE----------LVYDIVEEKQKQLEVE 95

  Fly   127 ----WIAHLEFSHNKEAAELSWEHVDVMLPRTEKLRNMVRQGIPHTLRAQMWMRLSGALAKKQKS 187
                |:..|:          |||    ....::||...:.:|||..||.|:|..|.. :.|.::.
Zfish    96 RTTKWLKMLK----------SWE----KYKNSDKLVRRIYKGIPLQLRGQVWCLLLD-IPKIKEE 145

  Fly   188 ETSYHDIVKASSNDQLMTSKQIEKDLLRILPTNACFSNPNGTGIPRLRRILRGIAWLFPDIGYCQ 252
            :..:::.:|..:.......:||:.|:.|....:..|.:........|..:|...:....::||||
Zfish   146 KKDFYEKLKIRARGLSPDVRQIDLDVNRTYRNHIMFMHRYDVKQQDLFHVLTAYSVYNTEVGYCQ 210

  Fly   253 GTGVIVACLLLFMEEENAFWMMATIVEDLLPASYYSSTLLG--------IQADQRVMHTLIANYL 309
            |...|.|.||::|.||:|||.:..::      |....|:.|        :...|.....::...:
Zfish   211 GMSQITALLLIYMNEEDAFWALVKLL------SGQRHTMHGFFVPGFPKLMRFQEHHDRILQKMM 269

  Fly   310 SSVDESLRKHDIELSLITLHWFLTLFANVVHMKILVRIWDWFFYEGSIVLFQLTLGMLKVKEQDL 374
            ..:.:.|...::..||.|:.||...|.:.....:.:||||.:..||..||..::..:||:.::.|
Zfish   270 PKLKQHLDNQEVYTSLYTMKWFFQCFLDRTPFTLTLRIWDIYILEGERVLTAMSYTILKLHKKTL 334

  Fly   375 KHLENS----------------------AQIFNSLSDI 390
            ..|...                      .|:.||:|::
Zfish   335 LKLSMEELVKFLQVTLSNDFFFEDDFVIEQLQNSMSEL 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	53/221 (24%)
		SH3_SGSM3	540..592	CDD:212747
		RUN	619..773	CDD:280855
usp6nl	XP_005164934.1	TBC	120..326	CDD:214540	51/212 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810