DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12241 and grtp1b

DIOPT Version :9

Sequence 1:	NP_650432.1	Gene:	CG12241 / 41834	FlyBaseID:	FBgn0038304	Length:	804	Species:	Drosophila melanogaster
Sequence 2:	NP_001017810.1	Gene:	grtp1b / 550508	ZFINID:	ZDB-GENE-050417-346	Length:	349	Species:	Danio rerio

Alignment Length:	335	Identity:	91/335 - (27%)
Similarity:	170/335 - (50%)	Gaps:	22/335 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 RFDEFGFRVEEEDGPEQSSNKLLSIPFVEDAQQRLQWIAHLEFSHNKEAAELSWEHVDVMLPRTE 155
            |.|::||  |:.|...:|..:|:|.......::..:|...|:.:...|              :..
Zfish    22 RVDQYGF--EKSDFNYESYEELMSDYLAVVTRRSKKWSKLLQGTGKME--------------KNL 70

  Fly   156 KLRNMVRQGIPHTLRAQMWMRLSGALAKKQKSETSYHDIVKASSNDQLMTSKQIEKDLLRILPTN 220
            |::..||:|||...|.::||..|||..:.:::...|..::|...:|..: .:.|..|:.|..|.|
Zfish    71 KVKRYVRKGIPCEHRTEIWMAFSGAQDQLERNPGYYQALLKTEQHDPKI-EEVIHADMHRTFPDN 134

  Fly   221 ACFSNPNGTGIPR-LRRILRGIAWLFPDIGYCQGTGVIVACLLLF-MEEENAFWMMATIVEDLLP 283
            ..|.:.:.:.:.: |..:|........|:|||||...|...||:. .:||.:||:|..::..:||
Zfish   135 IQFRHSSQSCLQKALFNVLLAYGHHNKDVGYCQGMNFIAGYLLIITKDEEKSFWLMVALIGRILP 199

  Fly   284 ASYYSSTLLGIQADQRVMHTLIANYLSSVDESLRKHDIELSLITLHWFLTLFANVVHMKILVRIW 348
             .||:.|:||::.||.|:..|:.:.:.:|.:::.:||:..:|:...||:.|:.:|:.::.::|||
Zfish   200 -DYYTQTMLGLKVDQEVLGELVKSKVPAVWQTMNQHDVMWTLVVSRWFICLYVDVLPVETVLRIW 263

  Fly   349 DWFFYEGSIVLFQLTLGMLKVKEQDLKHLENSAQIFNSLSDIP-GE-VTDVEVLFRQALEVGGSL 411
            |..|||||.:||::.|.:::..:..:...::..:|......|. || |.|.....::.....|.|
Zfish   264 DCLFYEGSKILFRVALTLIRHNQNLISQAKSLPEICEGFKQITRGEYVEDCHSFMQKIFMEPGGL 328

  Fly   412 SQTVIDTHRR 421
            |...|...|:
Zfish   329 STATITKLRK 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	67/215 (31%)
		SH3_SGSM3	540..592	CDD:212747
		RUN	619..773	CDD:280855
grtp1b	NP_001017810.1	TBC	76..289	CDD:214540	67/214 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1162786at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R540
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850