Protein Alignment CG12241 and rabgap1l

DIOPT Version :9

• Sequence 1: NP_650432.1
• Gene: CG12241 / 41834
• FlyBaseID: FBgn0038304
• Length: 804
• Species: Drosophila melanogaster
• Sequence 2: NP_001361730.1
• Gene: rabgap1l / 550007
• XenbaseID: XB-GENE-483580
• Length: 1056
• Species: Xenopus tropicalis
• Alignment Length: 554
• Identity: 119/554 - (21%)
• Similarity: 211/554 - (38%)
• Gaps: 114/554 - (20%)

  Fly    15 YVGREEHT----RKLQ---NLGSEDDLGELPPMMEELSVADGLRPNPGGPFSALTASMWPQEILA 72
            |..|:..|    .||:   |:|..|.:.|:..:..:..:.:.    |..|.||...|. |||
 Frog   419 YFSRKAFTDTFYLKLKPSGNIGVTDSMYEVVSLQRQSEIEEA----PTSPLSASNLSS-PQE--- 475

  Fly    73 KLGGGAELASGPNDQPEYRFDE---FGFRVEEEDGPEQSSNKLLSIPFVED--AQQRLQWIAHLE 132
                        .|.||...|.   .|.....:|.|||          :.|  .|..::|.::|.
 Frog   476 ------------EDDPEEESDTELWSGTGDVSKDCPEQ----------ILDCWGQLLVKWHSNLS 518

  Fly   133 FSHNKEAAELSWEHVDVMLPRTEKLRNMVRQGIPHTLRAQMWMRLSGALAKKQKSETSYHDIVKA 197
            .                   :.:.|.::|::|||..|||::|..|:|....::..:.....:||.
 Frog   519 V-------------------KPKGLSSLVKRGIPEALRAEVWQLLAGCHENQEMLDKYKMLVVKD 564

  Fly   198 SSNDQLMTSKQIEKDLLRILPTNACFSNPNGTGIPRLRRILRGIAWLFPDIGYCQGTGVIVACLL 262
            |:.|.:     |.:|:.|..|.:..|.|..|.|...|.::.:..:.....||||||...:.|.||
 Frog   565 SAQDSV-----IRRDIHRTFPAHDYFKNTEGDGQESLYKMCKVYSLYDEVIGYCQGMSFLAAVLL 624

  Fly   263 LFMEEENAFWMMATIVEDLLPASYYSSTLLGIQADQRVMHTLIANYLSSVDESLRKHDIELSLIT 327
            |.|.||.||.::..|:.|....:.|.:....:......:..|:...|..:.......::|..:..
 Frog   625 LHMPEEQAFCVLVKIMYDYQFRNLYQNNFEDLHCKFYQLERLLQEQLPDLYSHFVALNLEAHMYA 689

  Fly   328 LHWFLTLFANVVHMKILVRIWDWFFYEGSIVLFQLTLGMLKVKEQDLKHLENSAQIFNSLSDIPG 392
            ..|||:||.....:.::..|.|....||..::|.:.|.:||..::||..           :|..|
 Frog   690 SQWFLSLFTAKFPLCMVFHIMDLLLSEGLSIIFHVALALLKTSKEDLLQ-----------ADFEG 743

  Fly   393 EVTDVEVLFRQALEVGGSLSQTVIDTHRRRHLAYLMADQGHQIGNP-EAAPNLPKQQLARRQVRK 456
            .:.    .||..|.          ..:|....|..:.:|...|..| :......|:.||.|
 Frog   744 ALK----FFRVQLP----------KRYRAEENARRLMEQACNIKVPTKKLKKFEKEYLAMR---- 790

  Fly   457 SKSILEAFLFRGDGNEGDQLKNKNIRQTEILVDLREAILKVGRHFITIEPKLAGHIQLTANYSTE 521
                 |:.|.:.|..|..:.:|:.:::|.:.::.....|  ....:|.:..|...:
 Frog   791 -----ESQLQQEDPIERYKKENRRLQETSMRLEQENDDL--AHELVTSKIALRNDL--------- 839

  Fly   522 SHAKDHENFIN--VARTRKRRAKALHDFERHDDD 553
            ..|:|....:|  :..|::|..:|..:..:.:::
 Frog   840 DQAEDKAEVLNKELLLTKQRLVEAEEEKRKQEEE 873

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	58/213 (27%)
		SH3_SGSM3	540..592	CDD:212747	1/14 (7%)
		RUN	619..773	CDD:280855
rabgap1l	NP_001361730.1	PTB_Rab6GAP	123..251	CDD:269922
		DUF3694	284..415	CDD:372133
		TBC	528..737	CDD:214540	58/213 (27%)
		Smc	753..>1011	CDD:224117	24/151 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910