DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12241 and TBC1D13

DIOPT Version :9

Sequence 1:NP_650432.1 Gene:CG12241 / 41834 FlyBaseID:FBgn0038304 Length:804 Species:Drosophila melanogaster
Sequence 2:NP_060671.3 Gene:TBC1D13 / 54662 HGNCID:25571 Length:400 Species:Homo sapiens


Alignment Length:396 Identity:81/396 - (20%)
Similarity:123/396 - (31%) Gaps:160/396 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly   155 EKLRNMVRQGIP--HTLRAQMWMRLSGALAKKQKSETS------------------YHDIVKAS- 198
            ||||.:...|||  ..||...|..|...|..::.|.||                  ...|.||: 
Human    24 EKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWTSILAKQRELYAQFLREMIIQPGIAKANM 88

  Fly   199 ---------------------------SNDQLMTSKQIEKDLLRILPTNACF------------- 223
                                       .|:.|:   ||:||:.|:.|..:.|             
Human    89 GVSREDVTFEDHPLNPNPDSRWNTYFKDNEVLL---QIDKDVRRLCPDISFFQRATDYPCLLILD 150

  Fly   224 --------------------------------SNPNGTGIPR------------------LRRIL 238
                                            |:|:...:|.                  :.|||
Human   151 PQNEFETLRKRVEQTTLKSQTVARNRSGVTNMSSPHKNSVPSSLNEYEVLPNGCEAHWEVVERIL 215

  Fly   239 RGIAWLFPDIGYCQGTGVIVACL-LLFMEEENAFWMMATIVEDLLPASYYSSTLLGIQADQRVMH 302
            ...|.|.|.|.|.||...||..| ..|..:.|:.|.     |.....:::..|        .:|.
Human   216 FIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWK-----EHAEADTFFCFT--------NLMA 267

  Fly   303 TLIANYLSSVDES--------------LRKHDIELSL-----------ITLHWFLTLFANVVHMK 342
            .:..|::.|:|:|              |:..|:||.|           ....|...|.:....:.
Human   268 EIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLP 332

  Fly   343 ILVRIWDWFFYEGSIVLFQLTL--GMLKVKEQDLKHLENSAQI-FNSLSDIPGEVTDVEVLFRQA 404
            .::||||..|.:.:...|.|.:  .||.:..:.|  ||....: ...|.|.|  :|||..:.::|
Human   333 DVIRIWDSLFADDNRFDFLLLVCCAMLMLIREQL--LEGDFTVNMRLLQDYP--ITDVCQILQKA 393

  Fly   405 LEVGGS 410
            .|:..|
Human   394 KELQDS 399

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12241NP_650432.1 TBC 161..375 CDD:214540 65/352 (18%)
SH3_SGSM3 540..592 CDD:212747
RUN 619..773 CDD:280855
TBC1D13NP_060671.3 TBC 32..367 CDD:214540 66/352 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5210
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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