DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12241 and CG5916

DIOPT Version :9

Sequence 1:	NP_650432.1	Gene:	CG12241 / 41834	FlyBaseID:	FBgn0038304	Length:	804	Species:	Drosophila melanogaster
Sequence 2:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster

Alignment Length:	322	Identity:	89/322 - (27%)
Similarity:	154/322 - (47%)	Gaps:	28/322 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 DEFGFRVEEEDGPEQSSNKLLSIPFVEDAQQRLQWIAHLEFSHNKEAAELSWEHVDVMLPRTEKL 157
            ||:||: ..:.....:.:|.:........::|::|.|.|:  .|.:..:     ||.      ||
  Fly    13 DEYGFK-RGDHFDYNNYSKFMDGYLKTLTRRRMKWEAILQ--QNTDLTQ-----VDA------KL 63

  Fly   158 RNMVRQGIPHTLRAQMWMRLSGALAKKQKSETSYHDIVKASSNDQLMTSKQIEKDLLRILPTNAC 222
            :..:|:|||...|..:||::|||.|.:::|...:.::::....|:.: |..|..||.|..|.|..
  Fly    64 KRYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEPFDKEI-SDSISIDLPRTFPDNIH 127

  Fly   223 FSNPNGTGIPRLRRILRGIAWLFPDIGYCQGTGVIVACLLLFM-EEENAFWMMATIVEDLLPASY 286
            |....    .||..||...|....|:|||||...|...||:.. :||.:||::..|||:::| .|
  Fly   128 FDMKK----QRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTDDEEKSFWLLKHIVENIVP-QY 187

  Fly   287 YSSTLLGIQADQRVMHTLIANYLSSVDESLRKHDIELSLITLHWFLTLFANVVHMKILVRIWDWF 351
            :|..:..:..|..|...|:...:.:|:..:....:...:|...||:.:||.|:.::.::||||..
  Fly   188 HSHNMANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWFICIFAEVLPVETVLRIWDCV 252

  Fly   352 FYEGSIVLFQLTLGMLKVKEQDLKHLENSAQIFNSLSDI---PGEVTD----VEVLFRQALE 406
            |.||..::|:..|.|....:..:...::.|.:.|...|.   ...|||    ||.:|...|:
  Fly   253 FAEGYKIVFRAALTMFVTHKNAILGCDDIAALANLFRDTMIQDNIVTDCHGFVEAMFSLRLK 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	65/214 (30%)
		SH3_SGSM3	540..592	CDD:212747
		RUN	619..773	CDD:280855
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	65/214 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456634
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1162786at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R540
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.880