DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12241 and TBC1D3C

DIOPT Version :9

Sequence 1:NP_650432.1 Gene:CG12241 / 41834 FlyBaseID:FBgn0038304 Length:804 Species:Drosophila melanogaster
Sequence 2:XP_006721967.1 Gene:TBC1D3C / 414060 HGNCID:24889 Length:610 Species:Homo sapiens


Alignment Length:402 Identity:88/402 - (21%)
Similarity:148/402 - (36%) Gaps:103/402 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   104 GPEQ---SSNKLLSIPFVE---------DAQQ-------RLQWIAHLEFSHNKEAAELSWEHVDV 149
            ||.|   ||:.|..:|:.|         :|:|       :.:|:..|.          .||    
Human    97 GPLQAPCSSSALPGLPYSETELPPLTAREAKQIRREISRKSKWVDMLG----------DWE---- 147

  Fly   150 MLPRTEKLRNMVRQGIPHTLRAQMWMRLSGALAKKQKSETSYHDIVKASSNDQLMTSKQIEKDLL 214
            ....:.||.:...:|:|..:|..||..|......|.|:...| .|:|..........::|::|:.
Human   148 KYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRY-QIMKEKGKRSSEHIQRIDRDVS 211

  Fly   215 RILPTNACFSNPNGTGIPRLRRILRGIAWLFPDIGYCQGTGVIVACLLLFMEEENAFWMMATIVE 279
            ..|..:..|.:..||....|..||.......|::|||:....|.|..||::.||:|||.:.    
Human   212 GTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALV---- 272

  Fly   280 DLLPASYYS---------STLLGIQADQRVMHTLIANYLSSVDESLRKHDIELSLITLHWFLTLF 335
            .||.:..:|         .|:.|:|..|.  |.:..:...::....:| |:......|...:.:.
Human   273 QLLASERHSLQGFHSPNGGTVQGLQDQQE--HVVATSQPKTMGHQDKK-DLCGQCSPLGCLIRIL 334

  Fly   336 ANVVHMKILVRIWDWFFYEGSIVLFQLTLGMLKV--------------------------KEQD- 373
            .:.:.:.:.:|:||.:..||...|..:|....||                          :::| 
Human   335 IDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDT 399

  Fly   374 -LKHLENS-AQIFNSLSDIPGEVTDVEVLFRQALEVGGSLSQTVIDTHRRRHLAYLMADQGHQI- 435
             ||||..| .::.....|:|.....         |.|.|.|:.|            .|.:|.:. 
Human   400 VLKHLRASMKKLTRKKGDLPPPAKP---------EQGSSASRPV------------PASRGGKTL 443

  Fly   436 --GNPEAAPNLP 445
              |:.:|.|..|
Human   444 CKGDRQAPPGPP 455

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12241NP_650432.1 TBC 161..375 CDD:214540 54/250 (22%)
SH3_SGSM3 540..592 CDD:212747
RUN 619..773 CDD:280855
TBC1D3CXP_006721967.1 TBC 160..373 CDD:214540 53/220 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5210
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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