DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12241 and grtp1a

DIOPT Version :9

Sequence 1:	NP_650432.1	Gene:	CG12241 / 41834	FlyBaseID:	FBgn0038304	Length:	804	Species:	Drosophila melanogaster
Sequence 2:	NP_998567.1	Gene:	grtp1a / 406711	ZFINID:	ZDB-GENE-040426-2733	Length:	356	Species:	Danio rerio

Alignment Length:	370	Identity:	93/370 - (25%)
Similarity:	172/370 - (46%)	Gaps:	41/370 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 SGPNDQPEYRF-------------DEFGFRVEEEDGPEQSSNKLLSIPFVEDAQQRLQWIAHLEF 133
            :|...||::|.             |.:||: ..:|...::..:|:|.......::.::|...|:
Zfish     7 TGRTGQPQHRINQPSTARERANSVDAYGFQ-RSDDFDYETHEQLMSEYLAVLTRRSIRWAKLLQ- 69

  Fly   134 SHNKEAAELSWEHVDVMLPRTEKLRNMVRQGIPHTLRAQMWMRLSGALAKKQKSETSYHDIVKAS 198
                     ....||    |..|::..||:|:|:..|..:||..|||..:..::...|..::...
Zfish    70 ---------GRRRVD----RNLKVKRYVRKGVPNEHRPLVWMVCSGAQEQMDRNPGYYQSLLDTH 121

  Fly   199 SNDQLMTSKQIEKDLLRILPTNACFSNPNGTGIPRLRRILRGIAWLF----PDIGYCQGTGVIVA 259
            ...:|  .:.|..||.|..|.|..|..   :..|.|::.|..:...:    ..:|||||...|..
Zfish   122 HEPKL--EESIRTDLHRTFPDNIYFRK---SAEPCLQQALYNVLVAYGHHNKAVGYCQGMNFIAG 181

  Fly   260 CLLLF-MEEENAFWMMATIVEDLLPASYYSSTLLGIQADQRVMHTLIANYLSSVDESLRKHDIEL 323
            .|:|. .:||.:||:|..::..:|| .||:..:||::.||.|:..|:.....:|.:.::...:..
Zfish   182 YLILVSKDEETSFWLMEALLSRILP-DYYTPAMLGLKTDQEVLGELVRLKAPAVWKLMQDQGVMW 245

  Fly   324 SLITLHWFLTLFANVVHMKILVRIWDWFFYEGSIVLFQLTLGMLKVKEQDLKHLENSAQIFNSLS 388
            :|:...||:.||.:|:.::.::||||..|||||.:||::.|.:::..:|::...:|...:.....
Zfish   246 TLVVSRWFICLFIDVLPVETVLRIWDCLFYEGSKILFRVALTLIRHHQQEIAEAQNLPDVCERFK 310

  Fly   389 DIP--GEVTDVEVLFRQALEVGGSLSQTVIDTHRRRHLAYLMADQ 431
            .|.  ..|.|.....::..:..||||...:...|....|.::||:
Zfish   311 RITRGAFVEDCHTFMQKIFQEPGSLSMATVSKLRESCRARIIADE 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	65/218 (30%)
		SH3_SGSM3	540..592	CDD:212747
		RUN	619..773	CDD:280855
grtp1a	NP_998567.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..29		4/21 (19%)
grtp1a	NP_998567.1	TBC	84..296	CDD:214540	65/217 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1162786at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R540
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.950