Protein Alignment CG12241 and tbc1d5

DIOPT Version :9

• Sequence 1: NP_650432.1
• Gene: CG12241 / 41834
• FlyBaseID: FBgn0038304
• Length: 804
• Species: Drosophila melanogaster
• Sequence 2: NP_001315187.1
• Gene: tbc1d5 / 393583
• ZFINID: ZDB-GENE-040426-1197
• Length: 863
• Species: Danio rerio
• Alignment Length: 677
• Identity: 124/677 - (18%)
• Similarity: 233/677 - (34%)
• Gaps: 255/677 - (37%)

  Fly   122 QQRLQWIAHLEFSHNKEAAELSWEHV----------DVMLP---------------RTEKLRNMV 161
            :.:.|||:..: .|..:..::...|:          |:::.               :.::||.|:
Zfish    92 EDKAQWISRTK-EHRAQYEKIKEMHITNPRKAAGQQDLVVNNPLSQDEGSLWNKFFQDKELRGMI 155

  Fly   162 RQGIPHTLRAQMWMRLSGALAKKQKSETSYHDIV--KASSNDQLMTSKQIEKDLLRILPTNAC-- 222
            :|.:..|....::.       :::...|...||:  .|..|:||:..:.:.:.|..|:....|
Zfish   156 KQDVLRTFPEMLYF-------QEEDVRTKMTDILFCYARENEQLLYKQGMHELLAPIVFVLHCDH 213

  Fly   223 --FSNPNGTGIPR-LRRILRGIAWLFPDIGYCQGTGVIVACLLLFMEEENAFWMMATIVEDLLPA 284
              |.:.:.|..|. ..::|     |.|.                 ..|.:|:.|.:.::|...|
Zfish   214 QAFQHASETANPSDEMKVL-----LDPK-----------------FHEHDAYTMFSLLMETAEP- 255

  Fly   285 SYYSSTLLGIQADQRVMHTLI-----------------ANYLSSVDESLRKHDIEL--------- 323
             ::||....::..:..|.|.|                 .|.:.  |:.::||||||
Zfish   256 -WFSSFEREVRKGKEEMLTSIPFARPQDSGPSVAIVTKVNRIQ--DQLIKKHDIELYMHLNRLEI 317

  Fly   324 --SLITLHWFLTLFANVVHMKILVRIWDWFFYEGSIVL----------------------FQLTL 364
              .:..:.|...||.....::.|:.:||..|.: ||.|                      ||..|
Zfish   318 APQIYGIRWVRLLFGREFPLQDLLVVWDALFAD-SITLDLVDYVFVAMLLYIRDALIASNFQTCL 381

  Fly   365 GMLKVKEQDLKHLENSAQIFN------SLSDIPGEVTDVEVLFRQALEV----GGSL-------- 411
            |:       |.|......|.:      .|.|.......|...|:|.|:.    |..|
Zfish   382 GL-------LMHYPPIGDIHSLLLKALFLRDPKNNPRPVNYQFQQNLDYYKTRGADLVNKTRAST 439

  Fly   412 ----------SQTVIDTHRRRHLAYLMADQGHQIG-----NPE--AAPNLPKQQLARRQVRKSKS 459
                      |.::::..|:     |:|..|...|     |.|  :||.||..  |.|.:.::.|
Zfish   440 KAAPLNINKVSSSLLNFGRK-----LIAPMGGGSGGISPINSEVLSAPPLPAP--ASRPLTEAPS 497

  Fly   460 ILEAFLFRGDGNEGDQLKNKNIRQTE----------ILVDLREAILKVGRHFIT----IEPKLAG 510
            .....        ..|:|::.:.||:          :.|.|.:.:...|...|:    |...:.|
Zfish   498 CPAPL--------NTQMKSQPLPQTQHQHRLLKSESMPVHLSKDVGSCGASQISLPAQIHSDITG 554

  Fly   511 HIQLT--ANYSTE--SHAKDH---------------------------ENFINVARTRKRRAKAL 544
            |...|  ::.|||  |.::||                           ::|.|::|:|. .:|.:
Zfish   555 HSSRTVSSSPSTESLSCSRDHAMSSPPLPVSRGRDSSTSSPPSSATKKDSFFNISRSRS-HSKTI 618

  Fly   545 HDFERHDDDELGFRRNDIITIISQKDEHCWVGELNGLRGW--FPAKFV-------------ELLD 594
            :   :.|.:||..:    ::.:.        |::|.|...  :.||.:             |.|:
Zfish   619 N---KKDAEELEAQ----VSFLQ--------GQINDLEAMSKYCAKMMNAHIGKIQDVILQEHLE 668

  Fly   595 ERSKLYTS-AGDDAISETVTDLVRGTL 620
            :..::..| ||    .:.:.|:::|.|
Zfish   669 KEDEVLVSLAG----LKQIKDILKGAL 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	50/270 (19%)
		SH3_SGSM3	540..592	CDD:212747	9/66 (14%)
		RUN	619..773	CDD:280855	1/2 (50%)
tbc1d5	NP_001315187.1	TBC	71..373	CDD:214540	55/315 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900