Protein Alignment CG12241 and GAPcenA

DIOPT Version :9

• Sequence 1: NP_650432.1
• Gene: CG12241 / 41834
• FlyBaseID: FBgn0038304
• Length: 804
• Species: Drosophila melanogaster
• Sequence 2: NP_001097549.1
• Gene: GAPcenA / 38945
• FlyBaseID: FBgn0035879
• Length: 1194
• Species: Drosophila melanogaster
• Alignment Length: 625
• Identity: 130/625 - (20%)
• Similarity: 232/625 - (37%)
• Gaps: 166/625 - (26%)

  Fly    99 VEEEDGPEQSSNKL-------------LSIPFVEDAQQRLQWIAHLEFSH-------------NK 137
            :.|:.|.:|||:.|             .||..:||.       ...::|.             :|
  Fly   563 ITEQPGHQQSSSLLKMGMNNLSRIVRSSSIASIEDD-------CPSDYSSDGDEPLLSGTGEVSK 620

  Fly   138 EAAELSWEHVDVML------PRTEKLRNMVRQGIPHTLRAQMWMRLSGALAKKQKSETSYHDIVK 196
            :.::.:.:..|.:|      .|.:.|..:||.|:|..||.::|.:|:....:.:.:: .|..::.
  Fly   621 DCSQDTLDEWDPILREWDSEKRPKNLAPLVRLGVPEALREKIWQKLANVEGRMEMND-KYKILIT 684

  Fly   197 ASSNDQLMTSKQIEKDLLRILPTNACFSNPNGTGIPRLRRILRGIAWLFPDIGYCQGTGVIVACL 261
            ..:..:.:    |::|:.|..|.:.||....|:|...|.::.:..|....::|||||...|.|.|
  Fly   685 KETKCETV----IQRDIHRTFPAHKCFKEIGGSGQDALFKVSKAYAVHDSEVGYCQGLSFIAASL 745

  Fly   262 LLFMEEENAFWMMATI-----VEDLLPASYYSSTLLGIQADQRVMHTLIANYLSSVDESLRKHDI 321
            ||.|.||:||.::..:     :.||..|.:   .:|.::..|  :..||.:.|..:.|......|
  Fly   746 LLHMPEEDAFCVLVALMYDYGLRDLYKAGF---EVLYLRLYQ--LERLIKDQLPKLHEHFTACGI 805

  Fly   322 ELSLITLHWFLTLFANVVHMKILVRIWDWFFYEGSIVLFQLTLGMLKVKEQDLKHLENSAQIFNS 386
            |..:....|||||:.....:..:..:.|.|..:|..||||:.:.:|.:.|.||:.|:     |..
  Fly   806 ETHMYASQWFLTLYTARFPLCFVFHVLDVFLLDGLPVLFQVAVTLLSICESDLRQLD-----FEG 865

  Fly   387 LSDIPGEVTDVEVLFRQALEVGGSLSQTVIDTHRRRHLAYLMADQGHQIGNPEAAPNLPKQQLAR 451
            :                                    |.|.......:..:...|..:.| |...
  Fly   866 I------------------------------------LKYFRVTLPKKCRSSSQARKVMK-QACE 893

  Fly   452 RQVRKSKSILEAFLFRGDGNEGDQLKNKNIRQTEILVDLREAILKVGRHFITIEPKLAGHI---- 512
            |:::|.|...|.||          ||.::..:.|     :||.:...| |.....|:...|
  Fly   894 RKIKKLKQYEEEFL----------LKKQHKERLE-----KEAQIYENR-FGEERRKMQAEIDALN 942

  Fly   513 -QLT-ANYSTESHAKDHENFINVARTRKRRAKALHDFERHDDDELGFRRNDIITIISQKDEHCWV 575
             ||| |........|.|...|       :..|.:...:..|.:.|......::.::|...: |
  Fly   943 KQLTSAKERAVEKEKKHTGII-------QEYKQIIQRQEQDMNTLSETLGKVMHMVSNCQD-C-- 997

  Fly   576 GELNGLRGWFPAKFVELLDERSKLYTSAGDDAISETVTDLVRGTLAPAIKAFLEHGMKRPTFLGG 640
                       .:.::..::.:|     .||..:...||.:|..        .||.:       |
  Fly   998 -----------QQQIDAGNDNAK-----SDDGKNRGQTDAMRNA--------NEHPL-------G 1031

  Fly   641 PIHPWLYIEEAATREVEKDFESVYSRLVL----CKTYRLD 676
            |:.|   :..|:.|..|.:.|...::|..    ||...|:
  Fly  1032 PLDP---LNAASQRIRELELELAQAKLAQVEAECKNQDLN 1068

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	60/218 (28%)
		SH3_SGSM3	540..592	CDD:212747	5/51 (10%)
		RUN	619..773	CDD:280855	13/62 (21%)
GAPcenA	NP_001097549.1	PTB_Rab6GAP	204..332	CDD:269922
		DUF3694	429..523	CDD:289256
		TBC	650..858	CDD:214540	59/217 (27%)
		Phage_Gp23	<914..991	CDD:287621	17/89 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456590
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840