DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12241 and Grtp1

DIOPT Version :9

Sequence 1:	NP_650432.1	Gene:	CG12241 / 41834	FlyBaseID:	FBgn0038304	Length:	804	Species:	Drosophila melanogaster
Sequence 2:	NP_001163948.1	Gene:	Grtp1 / 361180	RGDID:	1309210	Length:	342	Species:	Rattus norvegicus

Alignment Length:	346	Identity:	97/346 - (28%)
Similarity:	168/346 - (48%)	Gaps:	28/346 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 RFDEFGFRVEEEDGPEQSSNKLLSIPFVEDAQQRLQWIAHLEFSHNKEAAELSWEHVDVMLPRTE 155
            |.|.:||. ..||....:..:..|...|...::.::|...|:.|..              :.::.
  Rat    16 RIDPYGFE-RPEDFDYAAYEEFFSTYLVILTKRAIKWSKLLKGSGG--------------VRKSV 65

  Fly   156 KLRNMVRQGIPHTLRAQMWMRLSGALAKKQKSETSYHDIVKASSNDQLMTSKQIEKDLLRILPTN 220
            .::..||:|||...||::||.:|||.|:..::...||.:::..|:.:|  .:.|..||.|..|.|
  Rat    66 TVKRYVRKGIPLEHRARVWMAVSGAQAQMDQNPGYYHRLLEGESSSRL--EEAIRTDLNRTFPDN 128

  Fly   221 ACFSNPNGTGIPRLRRILRGIAWLF----PDIGYCQGTGVIVACLLLFME-EENAFWMMATIVED 280
            ..|..   |..|.|::.|..:...:    .|:|||||...|...|:|..: ||.:||::..:|..
  Rat   129 VMFRK---TADPCLQKTLYNVLLAYGLHNQDVGYCQGMNFIAGYLILITKNEEESFWLLDALVGR 190

  Fly   281 LLPASYYSSTLLGIQADQRVMHTLIANYLSSVDESLRKHDIELSLITLHWFLTLFANVVHMKILV 345
            :|| .|||..:||::.||.|:..|:...|.:|...:..|.:..:|:...||:.||.:::.::.::
  Rat   191 ILP-DYYSPAMLGLKTDQEVLAELVRMKLPAVAALMDGHGVLWTLLVSRWFICLFVDILPVETVL 254

  Fly   346 RIWDWFFYEGSIVLFQLTLGMLKVKEQDLKHLENSAQIFNSLSDI-PGE-VTDVEVLFRQALEVG 408
            ||||..|.|||.::|::.|.::|..::.:....:...|.:....| .|: ||:.....::.....
  Rat   255 RIWDCLFNEGSKIIFRVALTLIKQHQEFILEASSVPDICDKFKQITKGDFVTECHTFMQKIFSEP 319

  Fly   409 GSLSQTVIDTHRRRHLAYLMA 429
            ||||...|...|....|.|.|
  Rat   320 GSLSMATITRLRESCRAALQA 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	72/218 (33%)
		SH3_SGSM3	540..592	CDD:212747
		RUN	619..773	CDD:280855
Grtp1	NP_001163948.1	TBC	71..284	CDD:214540	72/218 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1162786at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920