Protein Alignment CG12241 and CG4041

DIOPT Version :9

• Sequence 1: NP_650432.1
• Gene: CG12241 / 41834
• FlyBaseID: FBgn0038304
• Length: 804
• Species: Drosophila melanogaster
• Sequence 2: NP_572197.4
• Gene: CG4041 / 31422
• FlyBaseID: FBgn0029736
• Length: 819
• Species: Drosophila melanogaster
• Alignment Length: 688
• Identity: 147/688 - (21%)
• Similarity: 230/688 - (33%)
• Gaps: 252/688 - (36%)

  Fly    12 HEGYVGREEHTRKLQNLGSEDDLGELP------------PMMEELSVADGLRPNPGGPFSALTA- 63
            ||.||..::..|:|    .|..|..||            |:.||:.:  .|:.....|.|..|.
  Fly   226 HERYVQMDQRLRQL----LESCLSVLPKRRPLPGELLEHPIFEEVLL--DLKKQKMQPLSPETEH 284

  Fly    64 -------------SMWPQEILAKLGGG---AELASGPNDQPEYRFDEFGFRVEEEDGPEQSSNKL 112
                         .:|      :|.||   |||                    :::|..:|...:
  Fly   285 LPLLLRCPLSQIYHLW------QLAGGDVQAEL--------------------KKEGLIRSEAPI 323

  Fly   113 LSIPFV------------EDAQ---------------QRLQWI---------------AHLEFSH 135
            |.:|.:            ..||               |||..:               ||  |:.
  Fly   324 LGLPQIVRLSGASVCPGRSQAQLMDDRVVPLRLKALLQRLSGLPAAVYFPLLHSPRFPAH--FAR 386

  Fly   136 NKEAAELSWEHVDVMLPRTEKLRNMVR--QGIPHT---------------LRAQMWMRL-----S 178
            ..:...|.....|:.. :.:::|...|  ||.|||               ||..:|..|     :
  Fly   387 ELQELPLVIREKDIEY-QFQRVRLFARLLQGYPHTAEQLQREAAVDVPPLLRGPIWAALLEVVPN 450

  Fly   179 GALAKKQK-SETSYHDIVKASSNDQLMTSKQIEKDLLRILPTNACFSNPNGTGIPRLRRILRGIA 242
            |:.||..| :.||              |.:|||.|:.|....:...|:|:|.  .:|||:|:  |
  Fly   451 GSYAKIDKFTSTS--------------TDRQIEVDIPRCHQYDELLSSPDGH--RKLRRLLK--A 497

  Fly   243 WL--FPDIGYCQGTGVIVACLLL--FMEEENAFWMMATIVEDLLPASYYSSTLLGIQADQRVMHT 303
            |:  .|...|.||...:.|..|.  |..||.||..:...:...|...:....           ..
  Fly   498 WVTAHPQYVYWQGLDSLTAPFLYLNFNNEELAFLSLFKFIPKYLQWFFLKDN-----------SA 551

  Fly   304 LIANYLSSVDESLRKHDIELS-----------LITLHWFLTLFANVVHMKILVRIWD-------- 349
            :|..|||...:....|:..|:           |..:.||||:|::|..:..::.:||
  Fly   552 VIKEYLSKFSQLTAFHEPLLAQHLASISFIPELFAIPWFLTMFSHVFPLHKILHLWDKLMLGDSS 616

  Fly   350 WFFYEGSIVLFQLTLGMLKVKEQDLKHLENSAQIFNS----LSDIPGEVTDVEVLFRQALEVGGS 410
            :..:.|..:|.||...:|             ...||.    .||:|..|.|..||..|.:.....
  Fly   617 YPLFIGIAILRQLRSTLL-------------TSGFNECILLFSDLPDIVMDGCVLESQKMYEATP 668

  Fly   411 LSQTVIDTHRRRHLAYLMADQGHQIGNPEA-APNLPKQQLARRQVRKSKSILEAFLFRGDGNEGD 474
            .|.|     .|:|...|...|...||..:. ..:|.::|..|...:..:.:|:        |...
  Fly   669 KSIT-----HRQHALRLQPPQALDIGVADVELKHLQQEQCPRISAKDVQFLLD--------NSPA 720

  Fly   475 QLKNKNIRQTEILVDLREAILKVGR----HFITI--------------------EPKLAGHIQLT 515
            :|         .|:||| ::::.||    |.|.|                    |.:|.|.|.:.
  Fly   721 EL---------ALIDLR-SVVEFGRVHVPHSINIPFATVQLGEQRLEALQVPQLEAQLRGKIVVC 775

  Fly   516 ANYSTESHAKDHENFI---NVART--RKRRAKALHDFE 548
            .: :...|:.:..:|:   .|.||  ..:....||..|
  Fly   776 VS-NIHQHSVEFSHFLVACGVQRTCILHKGFNVLHSIE 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	63/259 (24%)
		SH3_SGSM3	540..592	CDD:212747	3/9 (33%)
		RUN	619..773	CDD:280855
CG4041	NP_572197.4	PKc_like	45..272	CDD:304357	14/51 (27%)
		TBC	432..634	CDD:214540	56/230 (24%)
		RHOD_Kc	706..810	CDD:238783	22/122 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456525
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940