Protein Alignment CG12241 and Rabgap1

DIOPT Version :9

• Sequence 1: NP_650432.1
• Gene: CG12241 / 41834
• FlyBaseID: FBgn0038304
• Length: 804
• Species: Drosophila melanogaster
• Sequence 2: NP_001101311.1
• Gene: Rabgap1 / 311911
• RGDID: 1304691
• Length: 1065
• Species: Rattus norvegicus
• Alignment Length: 615
• Identity: 141/615 - (22%)
• Similarity: 222/615 - (36%)
• Gaps: 175/615 - (28%)

  Fly    62 TASMWPQEILAKLGGGAELASGPNDQPEYRFDEFGFRVEEEDGPEQSSNKLLSIPFVEDAQQRLQ 126
            |||  |...|.:.|..:.:...|   ||   |:     ||||..|    .|||
  Rat   485 TAS--PSVRLPQSGSQSSMIPSP---PE---DD-----EEEDNDE----PLLS------------ 520

  Fly   127 WIAHLEFSH-NKEAAE---------LSWEHVDVMLPRTEKLRNMVRQGIPHTLRAQMWMRLSGAL 181
                 .|.. :||.||         ||..|:::.: |.::|.::||.|:|..||.::|..|:|..
  Rat   521 -----GFGDVSKECAEKILETWGELLSKWHLNLNV-RPKQLSSLVRSGVPEALRGEVWQLLAGCH 579

  Fly   182 AKKQKSETSYHDIVKASSNDQLMTSKQIEKDLLRILPTNACFSNPNGTGIPRLRRILRGIAWLFP 246
            ......|.....|.|.|..|..:|     :|:.|..|.:..|.:..|.|...|.:|.:..:....
  Rat   580 NNDHLVEKYRILITKESPQDSAIT-----RDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDE 639

  Fly   247 DIGYCQGTGVIVACLLLFMEEENAFWMMATIVEDL------------LPASYYSSTLLGIQADQR 299
            :||||||...:.|.|||.|.||.||.::..|:.|.            |...:|..        :|
  Rat   640 EIGYCQGQSFLAAVLLLHMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQL--------ER 696

  Fly   300 VMHTLIAN-YLSSVDESLRKHDIELSLITLHWFLTLFANVVHMKILVRIWDWFFYEGSIVLFQLT 363
            :|...|.: |...:|.||..|     :....||||||.....:.::..|.|....||..|:|.:.
  Rat   697 LMQEYIPDLYNHFLDISLEAH-----MYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVA 756

  Fly   364 LGMLKVKEQD--LKHLENSAQIFNSLSDIPGEVTDVEVLFR-QALEVGGSLSQTVIDTHRRRHLA 425
            ||:||..:.|  |...|.:.:.|.  ..:|......|...| ..|.....:||..:....:.:
  Rat   757 LGLLKTSKDDLLLTDFEGALKFFR--VQLPKRYRSEENAKRLMELACNTKISQKKLKKFEKEY-- 817

  Fly   426 YLMADQGHQIGNP--------------------------------------------EAAPNLPK 446
            :.|.:|..|..:|                                            |.|..|.|
  Rat   818 HTMREQQAQQEDPIERFERENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNK 882

  Fly   447 QQL------------ARRQVRKSKSILEAFLFRGDGNEGDQLKNKNI-----------------R 482
            :.|            .||...:|..:.|......|..|.:..||.:|                 :
  Rat   883 ELLMTKQKLIDAEDEKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQ 947

  Fly   483 QTEILVDLREAILKVG-----RHFITIEPKLAG--HIQLTANYSTESHAKDHEN-----FINVAR 535
            ||...|::.:...||.     |.|...|.::.|  .::..::..|:...:..:|     .:.:|:
  Rat   948 QTANKVEIEKIRQKVDDCDRCRDFFNKEGRVKGASSVKGVSDEDTDEEKETLKNQLRELELELAQ 1012

  Fly   536 TRKRRAKA---LHDFERHDDDELGFRRNDI 562
            |:.:..:|   :.|.|.|    ||...:::
  Rat  1013 TKLQLVEAECKIQDLEHH----LGLALSEV 1038

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	67/228 (29%)
		SH3_SGSM3	540..592	CDD:212747	6/26 (23%)
		RUN	619..773	CDD:280855
Rabgap1	NP_001101311.1	PTB_Rab6GAP	141..269	CDD:269922
		DUF3694	303..433	CDD:403614
		TBC	559..768	CDD:214540	67/226 (30%)
		ERM	790..1016	CDD:395622	36/227 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810