Protein Alignment CG12241 and Tbc1d9

DIOPT Version :9

• Sequence 1: NP_650432.1
• Gene: CG12241 / 41834
• FlyBaseID: FBgn0038304
• Length: 804
• Species: Drosophila melanogaster
• Sequence 2: XP_006255308.1
• Gene: Tbc1d9 / 304645
• RGDID: 1308221
• Length: 1262
• Species: Rattus norvegicus
• Alignment Length: 645
• Identity: 158/645 - (24%)
• Similarity: 254/645 - (39%)
• Gaps: 185/645 - (28%)

  Fly    30 SEDDLGELP-------PMMEELSVADGLRP-NPGGPFSALTASMWPQEILAKLGGGAELASGPND 86
            |:|::...|       |.....|.|||.|| |..|. |..||:   |.::..
  Rat   417 SDDEVYSRPSSLVSSSPQRSTSSDADGERPFNLNGN-SVPTAT---QTLMTM------------- 464

  Fly    87 QPEYRFDEFGFRVEEEDGPEQSSNKLLSIPFVEDAQQRLQWIAHL-EFSHNKEAAELSWEHVDVM 150
               ||          ...||:.:.||......|.|     |..|. |:...            :.
  Rat   465 ---YR----------RRSPEEFNPKLAKEFLKEQA-----WKIHFAEYGQG------------IC 499

  Fly   151 LPRTEKLRNMVRQGIPHTLRAQMWMRLSGALAKKQKSETSYHDIVKASSNDQLMTSKQIEKDLLR 215
            :.||||.|.:|.:|||..:|.::|:.||||:.:|......|.|:|:.|.....:.:::||:||.|
  Rat   500 MYRTEKTRELVLKGIPERMRGELWLLLSGAINEKATHPGYYEDLVEKSMGKYNLATEEIERDLHR 564

  Fly   216 ILPTNACFSNPNGTGIPRLRRILRGIAWLFPDIGYCQGTGVIVACLLLFMEEENAFWMMATIVED 280
            .||.:..|.|.  .||..|||:|...|:..|:|||||...::.:.|||:.:||.|||::..:.|.
  Rat   565 SLPEHPAFQNE--MGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLLVALCER 627

  Fly   281 LLPASYYSSTLLGIQADQRVMHTLIANYLSSVDESLRKHDIELSLITLHWFLTLFANVVHMKILV 345
            :|| .||::.::|...||.|...|..:|:..:.:.::...: :|.|:|.||||||.:|:..:..|
  Rat   628 MLP-DYYNTRVVGALVDQGVFEELARDYVPQLYDCMQDLGV-ISTISLSWFLTLFLSVMPFESAV 690

  Fly   346 RIWDWFFYEGSIVLFQLTLGMLKVKEQDL--------------KHLENSA----------QIFNS 386
            .:.|.|||||..|:|||.|.:|......|              ::|::..          .:.:.
  Rat   691 VVVDCFFYEGIKVIFQLALAVLDANVDKLLGCKDDGEAMTVLGRYLDSVTNKDSTLPPIPHLHSL 755

  Fly   387 LSDIPGEVTDVEVL----------------------FRQALEVGGSLSQTVIDTHRRRHLAYLMA 429
            |||..|....|::.                      |:|.|:|    .||:.||.:|..:..::.
  Rat   756 LSDDVGPYPAVDIFRLIGTSYEKFGTIRADLIEQMRFKQRLKV----IQTLEDTTKRNVVRTIVT 816

  Fly   430 DQGHQI---------------------GNPEAA----PNLPKQQLARRQVRKSK----------- 458
            :....|                     |:..|.    |:||..:..|....:.|
  Rat   817 ETSFTIDELEELYALFKAEHLTSCYWGGSSNAPDRHDPSLPYLEQYRIDFEQFKGMFVLLFPWAC 881

  Fly   459 ----SILEAFLFRGDGNEGDQLKN--------------------KNIRQTEIL------VDLREA 493
                .:|.:.||:.....||.|.|                    |.:.:..:|      .|..::
  Rat   882 GTHSDVLASRLFQLLDENGDSLINFREFVSGLSAACHGDLTEKLKLLYKMHVLPEPSCDQDEPDS 946

  Fly   494 ILKVGRHFI-TIEPKLAGHIQLTANYSTESHAKD--HENFINVARTRKRRAKALHDFERH 550
            ..:..::|. .|.|:....:.|      :|..|.  .|.|:.|:..:.|..:|.....||
  Rat   947 AFEATQYFFEDITPECTHVVGL------DSRGKQSADEGFVTVSLKQDRGKRANSQENRH 1000

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	80/227 (35%)
		SH3_SGSM3	540..592	CDD:212747	3/11 (27%)
		RUN	619..773	CDD:280855
Tbc1d9	XP_006255308.1	PH-GRAM1_TCB1D9_TCB1D9B	157..255	CDD:275420
		PH-GRAM2_TCB1D9_TCB1D9B	304..399	CDD:270161
		TBC	510..720	CDD:214540	79/213 (37%)
		EFh	<891..921	CDD:298682	6/29 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810