DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12241 and SPAC4G8.04

DIOPT Version :9

Sequence 1:	NP_650432.1	Gene:	CG12241 / 41834	FlyBaseID:	FBgn0038304	Length:	804	Species:	Drosophila melanogaster
Sequence 2:	NP_593064.1	Gene:	SPAC4G8.04 / 2543572	PomBaseID:	SPAC4G8.04	Length:	772	Species:	Schizosaccharomyces pombe

Alignment Length:	274	Identity:	88/274 - (32%)
Similarity:	150/274 - (54%)	Gaps:	5/274 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 RTEKLRNMVRQGIPHTLRAQMWMRLSGALAKKQKSETSYHDIVKASSNDQLMTSKQIEKDLLRIL 217
            |..|.|.:|:.|:|...:|::|:..|||.  :..|...|.:::..:...:..:..||:.|:.|.:
pombe   493 RWHKFRELVKNGVPLCYKAKVWLECSGAY--QLHSPGYYEELLSRTDEVESASVAQIDMDINRTM 555

  Fly   218 PTNACFSNPNGTGIPRLRRILRGIAWLFPDIGYCQGTGVIVA-CLLLFMEEENAFWMMATIVEDL 281
            ..|..|.. .|.|||:|||||...:...|.||||||..||.| .|||:..||:||:|:.:|:|::
pombe   556 AKNVFFGG-KGPGIPKLRRILVAYSRHNPHIGYCQGMNVIGAFLLLLYASEEDAFYMLMSIIENV 619

  Fly   282 LPASYYSSTLLGIQADQRVMHTLIANYLSSVDESLRKHDIELSLITLHWFLTLFANVVHMKILVR 346
            ||..|::..|:..:|||.|:.:.:...|..:...|....::|..|:.||||:::.:.:...|..|
pombe   620 LPPKYFTPDLMTSRADQLVLKSFVKESLPEIYSHLELLGVDLDAISFHWFLSVYTDTLPTNISFR 684

  Fly   347 IWDWFFYEGSIVLFQLTLGMLKVKEQDLKHLENSAQIFNSLSDIPGEVTDVEVLFRQALEVGGSL 411
            |:|..|.:|.:.||::.|.:||..:|.:....:|:.|::.|||:.......:...::|.:....|
pombe   685 IFDMLFCDGYVCLFRVALTILKSLKQQILACNSSSAIYSFLSDLVQYSFQPDSFIKEAADRWSKL 749

  Fly   412 SQTVIDTHRRRHLA 425
             .|.....|:|:||
pombe   750 -VTEKSIERKRNLA 762

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	73/214 (34%)
		SH3_SGSM3	540..592	CDD:212747
		RUN	619..773	CDD:280855
SPAC4G8.04	NP_593064.1	COG5210	212..732	CDD:227535	81/241 (34%)
SPAC4G8.04	NP_593064.1	TBC	501..713	CDD:214540	73/214 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR22957
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R540
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940