Protein Alignment CG12241 and tbc-6

DIOPT Version :9

• Sequence 1: NP_650432.1
• Gene: CG12241 / 41834
• FlyBaseID: FBgn0038304
• Length: 804
• Species: Drosophila melanogaster
• Sequence 2: NP_001021909.1
• Gene: tbc-6 / 182185
• WormBaseID: WBGene00015410
• Length: 330
• Species: Caenorhabditis elegans
• Alignment Length: 307
• Identity: 81/307 - (26%)
• Similarity: 141/307 - (45%)
• Gaps: 45/307 - (14%)

  Fly    93 DEFGF----RVEEEDGPEQSSNKLLS--IPFVEDAQQRLQWIAHLEFSHNKEAAELSWEHVDVML 151
            |:.||    ..:||.|.::......|  :|.|  .::|.:|        .||.
 Worm    21 DDLGFLRPWSPQEESGCKKQYEAWYSSYLPIV--VRRRCRW--------EKEN------------ 63

  Fly   152 PR--TEKLRNMVRQGIPHTLRAQMWMRLSGALAKKQKSETSYHDIVKASSNDQLMTSKQIEKDLL 214
            ||  :..|:..||:|||||.|.::|:|   :...:.......|::     .|:::  |||:.||.
 Worm    64 PRRNSHLLQRFVRKGIPHTFRKELWLR---SCPSRADGVWQRHEV-----PDEVI--KQIKLDLP 118

  Fly   215 RILPTNACFSNPNGTGIPRLRRILRGIAWLFPDIGYCQGTGVIVACLLLFMEEEN-AFWMMATIV 278
            |..|.|. |....||. ..|.|.|..:|...|.:|||||...:...:||.:.:|: |..::..:|
 Worm   119 RTFPDNK-FLKTEGTR-KTLGRALFAVAEHIPSVGYCQGLNFVAGVILLVVNDESRAIDLLVHLV 181

  Fly   279 EDLLPASYYSSTLLGIQADQRVMHTLIANYLSSVDESLRKHDIELSLITLHWFLTLFANVVHMKI 343
            ..  ...||...::|::.|..|:|:|:..:...|..:|.|.|:.|.::...||:..|...:.|:.
 Worm   182 SQ--RQEYYGKNMIGLRRDMHVLHSLLREHCPRVVVTLEKLDVGLDMLVGKWFVCWFVESLPMET 244

  Fly   344 LVRIWDWFFYEGSIVLFQLTLGMLKVKEQDLKHLENSAQIFNSLSDI 390
            ::|:||...|||...||::.:.:.:.....:...|:..|:...:.:|
 Worm   245 VLRLWDCLIYEGDEWLFRIAVALFRSNMIAISSCESIDQLMTEVQNI 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	62/214 (29%)
		SH3_SGSM3	540..592	CDD:212747
		RUN	619..773	CDD:280855
tbc-6	NP_001021909.1	RabGAP-TBC	99..272	CDD:278964	52/183 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1162786at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R540
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.850