DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12241 and tbc1d14

DIOPT Version :9

Sequence 1:	NP_650432.1	Gene:	CG12241 / 41834	FlyBaseID:	FBgn0038304	Length:	804	Species:	Drosophila melanogaster
Sequence 2:	XP_004911305.1	Gene:	tbc1d14 / 100489752	XenbaseID:	XB-GENE-991334	Length:	794	Species:	Xenopus tropicalis

Alignment Length:	371	Identity:	84/371 - (22%)
Similarity:	151/371 - (40%)	Gaps:	88/371 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 AELASGPNDQPEYRFDEFGFRVEEEDGPEQSSNKLLSIPFVEDAQQR---LQWIAHLEFSHNKEA 139
            |.|.:.|.::.:..      |:|.|:...|:..:..     :|||:|   |:....||.|...
Frog   422 ANLPAKPAEEAQKH------RLEYEEMVAQAKRREF-----KDAQRRKKQLEERCKLEESIGN-- 473

  Fly   140 AELSWEHVDVMLPRTE------KLRNMVRQGIPHTLRAQMWMRLSGALAKKQKSETSYHDIVKAS 198
            |.|:|.  ..:||..|      ::|:|..||||.::|.::|   |.|:..:.......:||..:.
Frog   474 AALTWN--TEILPNWETMCCSRRVRDMWWQGIPPSVRGRVW---SLAIGNELNITHDLYDICLSR 533

  Fly   199 SNDQL-----------------------MTSKQIEKDLLRILPTNACFSNPNGTGIPRLRRILRG 240
            :.|:.                       .:.:.|:.|:.|..| |.|.....|.....|..||..
Frog   534 AKDRWKSLSMGTQEADNEDSGLSVADREASLESIKLDISRTFP-NLCIFQRGGPYHDMLHSILGA 597

  Fly   241 IAWLFPDIGYCQGTGVIVACLLLFMEEENAFWMMATIVEDLLPASYYSSTLLGIQADQRVMHTLI 305
            .....||:||.||...|.|.|:|.::..:||...:.::......:::           ||.|.|:
Frog   598 YTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFF-----------RVDHGLM 651

  Fly   306 ANYLSS----VDESL-------RKHDIELSLITLHWFLTLFANVVHMKILVRIWDWFFYEGSIVL 359
            ..|.::    .:|:|       :|:::...:..:.|..||::..:.:.:..|:||.|..:|...|
Frog   652 LTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFL 716

  Fly   360 FQLTLGMLKVKEQDLKHLE---------------NSAQIFNSLSDI 390
            |...||:|::.|..|..::               ||..:|.|::.|
Frog   717 FSTALGILRLFEDILTRMDFIHIAQFLTKLPEDLNSEDLFASIAAI 762

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	55/247 (22%)
		SH3_SGSM3	540..592	CDD:212747
		RUN	619..773	CDD:280855
tbc1d14	XP_004911305.1	TBC	499..731	CDD:214540	55/246 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000