Protein Alignment CG12241 and sgsm3

DIOPT Version :9

• Sequence 1: NP_650432.1
• Gene: CG12241 / 41834
• FlyBaseID: FBgn0038304
• Length: 804
• Species: Drosophila melanogaster
• Sequence 2: NP_001123837.1
• Gene: sgsm3 / 100170594
• XenbaseID: XB-GENE-965522
• Length: 753
• Species: Xenopus tropicalis
• Alignment Length: 760
• Identity: 500/760 - (65%)
• Similarity: 628/760 - (82%)
• Gaps: 10/760 - (1%)

  Fly    46 VADGLRPNPGGPFSALTASMWPQEILAKLGGGAELASGPNDQPEYRFDEFGFRVEEEDGPEQSSN 110
            ::.|..|:|||.|||||||||||:||||.....:..    :|||:|:|||||||::|||.|.:|:
 Frog     1 MSGGYTPSPGGSFSALTASMWPQDILAKYTQKEQSV----EQPEFRYDEFGFRVDKEDGAEPNSS 61

  Fly   111 KLLSIPFVEDAQQRLQWIAHLEFSHNKEAAELSWEHVDVMLPRTEKLRNMVRQGIPHTLRAQMWM 175
            |||.||..||.||||:|.|||||:||.:..:|:|:.:||.||.::|||::|..||||::|.|:||
 Frog    62 KLLGIPLTEDPQQRLRWQAHLEFTHNHDVGDLTWDKIDVTLPHSDKLRSLVLAGIPHSMRPQLWM 126

  Fly   176 RLSGALAKKQKSETSYHDIVKASSNDQLMTSKQIEKDLLRILPTNACFSNPNGTGIPRLRRILRG 240
            ||||||.|||.||.:|.|||:.||||..:.:|||||||||.:|:||||||....|:|||||:|||
 Frog   127 RLSGALQKKQNSEMTYKDIVRNSSNDDTLAAKQIEKDLLRTMPSNACFSNLQSVGVPRLRRVLRG 191

  Fly   241 IAWLFPDIGYCQGTGVIVACLLLFMEEENAFWMMATIVEDLLPASYYSSTLLGIQADQRVMHTLI 305
            :|||:||||||||||::.||||||:|||:||||||.|||||:|.||:::||:|:|.||||:..||
 Frog   192 LAWLYPDIGYCQGTGMVAACLLLFLEEEDAFWMMAAIVEDLVPVSYFNTTLVGVQTDQRVLRHLI 256

  Fly   306 ANYLSSVDESLRKHDIELSLITLHWFLTLFANVVHMKILVRIWDWFFYEGSIVLFQLTLGMLKVK 370
            ..||..:|:.|::|||||||||||||||.||:|||:|:|:||||:|||:||:||||.||||||:|
 Frog   257 VQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVHIKLLLRIWDFFFYQGSLVLFQTTLGMLKMK 321

  Fly   371 EQDLKHLENSAQIFNSLSDIPGEVTDVEVLFRQALEVGGSLSQTVIDTHRRRHLAYLMADQGHQI 435
            |::|...||||.|||:|||||.::.:.:||.|:|:.:.|:|::.:|:..||:|||||:||||..:
 Frog   322 EEELIQSENSASIFNTLSDIPSQIEEADVLLREAMLISGTLTEVMIEAQRRKHLAYLIADQGQLL 386

  Fly   436 GNPEAAPNLPKQQLARRQVRKSKSILEAFLFRGDGNEGDQLKNKNIRQTEILVDLREAILKVGRH 500
            .:..|..||.|  :.|||.::.||.:...||..|..|.  ||:|||:||.::.|||||||:|.||
 Frog   387 NSTAAVTNLSK--IIRRQSQRRKSGITTLLFGDDDFEA--LKSKNIKQTALVADLREAILQVARH 447

  Fly   501 FITIEPKLAGHIQLTANYSTESHAKDHENFINVARTRKRRAKALHDFERHDDDELGFRRNDIITI 565
            |...:||... |.||.:|:.|||.:||||:::.:|:|:||||||.|||||||||||||:||||||
 Frog   448 FQCTDPKNCS-IDLTPDYTMESHQRDHENYVSCSRSRRRRAKALLDFERHDDDELGFRKNDIITI 511

  Fly   566 ISQKDEHCWVGELNGLRGWFPAKFVELLDERSKLYTSAGDDAISETVTDLVRGTLAPAIKAFLEH 630
            ||||||||||||||||||||||||||:||||||.|:.||||:::|.:||||||||.|:||:..||
 Frog   512 ISQKDEHCWVGELNGLRGWFPAKFVEILDERSKEYSVAGDDSVTEGITDLVRGTLCPSIKSIFEH 576

  Fly   631 GMKRPTFLGGPIHPWLYIEEAATREVEKDFESVYSRLVLCKTYRLDEDGKVLTPEELLYRCVQAI 695
            |:|:|:.||||.||||:|||||:||||:||:|||||||||||||||||||||||||||||.||::
 Frog   577 GLKKPSLLGGPCHPWLFIEEAASREVERDFDSVYSRLVLCKTYRLDEDGKVLTPEELLYRGVQSV 641

  Fly   696 NQTHDDAHAQMDVKLRSLICLGLNEQVLHLWLEVLCACQEVVQKWYHSWSFIDSPGWVQIKCELR 760
            |.:||.||||||||||||||:|||||||||||||||:....|:|||..|||:.||||||||||||
 Frog   642 NVSHDAAHAQMDVKLRSLICIGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCELR 706

  Fly   761 ILSQFAFNLNPDWELPPKR-GKESQPLKDGVRDMLVKHHLFSWDL 804
            :||:|||:|:||||||.|| .||.:|||:||:||||||||||||:
 Frog   707 VLSRFAFSLSPDWELPVKREDKEKKPLKEGVQDMLVKHHLFSWDI 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	146/213 (69%)
		SH3_SGSM3	540..592	CDD:212747	49/51 (96%)
		RUN	619..773	CDD:280855	118/153 (77%)
sgsm3	NP_001123837.1	TBC	115..326	CDD:214540	145/210 (69%)
		SH3_SGSM3	486..538	CDD:212747	49/51 (96%)
		RUN	565..716	CDD:367169	116/150 (77%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	311	1.000	Domainoid score	I1301
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9249
Inparanoid	1	1.050	1051	1.000	Inparanoid score	I257
OMA	1	1.010	-	-		QHG48054
OrthoDB	1	1.010	-	-		D1162786at2759
OrthoFinder	1	1.000	-	-		FOG0007050
OrthoInspector	1	1.000	-	-		oto103217
Panther	1	1.100	-	-	LDO	PTHR22957
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R540
SonicParanoid	1	1.000	-	-		X5135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110