Protein Alignment CG12241 and tbc1d9b

DIOPT Version :9

• Sequence 1: NP_650432.1
• Gene: CG12241 / 41834
• FlyBaseID: FBgn0038304
• Length: 804
• Species: Drosophila melanogaster
• Sequence 2: NP_001107313.1
• Gene: tbc1d9b / 100135104
• XenbaseID: XB-GENE-989754
• Length: 1259
• Species: Xenopus tropicalis
• Alignment Length: 552
• Identity: 135/552 - (24%)
• Similarity: 224/552 - (40%)
• Gaps: 138/552 - (25%)

  Fly    26 QNLGSEDDLGELPPMMEELSVADGLRPNPGGPFSALTASMWPQEILAKLGGGAELASGPNDQPEY 90
            ||.|.|:.....|....::|.......|.|.  .|.|||    ..|.||
 Frog   416 QNNGCEEATNPSPSSSTDVSPTFSTPQNNGS--DAPTAS----HGLLKL---------------- 458

  Fly    91 RFDEFGFRVEEEDGPEQSSNKLLSIPFVEDAQQRLQWIAH-LEFSHNKEAAELSWEHVDVMLPRT 154
                |...:.|:..|:....|:          :...|..| ||:...            :.:.||
 Frog   459 ----FQREITEDMKPKWDKEKM----------KEESWNIHFLEYGRG------------MCMYRT 497

  Fly   155 EKLRNMVRQGIPHTLRAQMWMRLSGALAKKQKSETSYHDIVKASSNDQLMTSKQIEKDLLRILPT 219
            .|.|.:|.:|||..||.::|:..|||..:.......|.|:|:.|.....:.:.:||:||.|.:|.
 Frog   498 SKTRELVLKGIPENLRGELWLLFSGASNEMVTHPGYYADLVEKSMGRCNLATDEIERDLHRSMPE 562

  Fly   220 NACFSNPNGTGIPRLRRILRGIAWLFPDIGYCQGTGVIVACLLLFMEEENAFWMMATIVEDLLPA 284
            :..|.|.  .||..|||:|...|:..|:|||||...::.:.|||:..||.|||::.::.|.:||
 Frog   563 HPAFQNE--LGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYCNEEEAFWLLVSLCEHMLP- 624

  Fly   285 SYYSSTLLGIQADQRVMHTLIANYLSSVDESLRKHDIELSLITLHWFLTLFANVVHMKILVRIWD 349
            .||::.::|...||.|...|...||..:.|.:::..: :|.|:|.||||||.:|:..:..|.:.|
 Frog   625 DYYNTRVVGALVDQGVFEELTRLYLPQLSEKMQELGV-ISTISLSWFLTLFLSVMPFESAVVVVD 688

  Fly   350 WFFYEGSIVLFQLTLGMLKVKEQDL--------------KHLENSAQIFNSLS------------ 388
            .||:||..::.||:|.:|:...:.|              ::|:|   :.|..|
 Frog   689 CFFFEGIKLILQLSLAVLEANMESLMNCMDEGEAMTILGRYLDN---VLNKQSVSPPIPHLHALL 750

  Fly   389 ----DIPGEV------------------TDVEVL-FRQALEVGGSLSQTVIDTHRRRHLAYLMAD 430
                :.|.||                  .|:|.: |:|.|:|    .|::.||.:|..:..:..|
 Frog   751 TIGDEPPPEVDIFELIEASYEKFSALRSDDIEQMRFKQRLKV----IQSLEDTAKRSIVRAISTD 811

  Fly   431 QGHQI---------------------GNPEAA----PNLPKQQLARRQVRKSKSILEAFLFRGDG 470
            .|..:                     ||..:.    |:||..:..|..:::.:.:.........|
 Frog   812 LGFSMEELEDLYVLFKAQHLMNCYWGGNRTSGSRHDPSLPYLEQYRIDLQQFQELFNQLTPWSCG 876

  Fly   471 NEGDQLKNKNIR----QTEILVDLREAILKVG 498
            .....|..:..|    ..:.|::.:|.:..:|
 Frog   877 QHAPILATRIFRLLDSNKDSLINFKEFVTGLG 908

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12241	NP_650432.1	TBC	161..375	CDD:214540	77/227 (34%)
		SH3_SGSM3	540..592	CDD:212747
		RUN	619..773	CDD:280855
tbc1d9b	NP_001107313.1	PH-GRAM1_TCB1D9_TCB1D9B	154..251	CDD:275420
		PH-GRAM2_TCB1D9_TCB1D9B	299..394	CDD:270161
		TBC	504..714	CDD:214540	76/213 (36%)
		EFh	<854..905	CDD:298682	6/50 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R540
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940