DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4210 and GNPNAT1

DIOPT Version :9

Sequence 1:NP_650430.1 Gene:CG4210 / 41832 FlyBaseID:FBgn0038302 Length:174 Species:Drosophila melanogaster
Sequence 2:NP_932332.1 Gene:GNPNAT1 / 64841 HGNCID:19980 Length:184 Species:Homo sapiens


Alignment Length:144 Identity:33/144 - (22%)
Similarity:53/144 - (36%) Gaps:36/144 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 VLSMIQELADFEKMSNGPQ---LTEEDLKRDAGLTGGQEYCEVYVLVDNDTDQAIGYSICYKAYS 81
            |:|..|.:..||.|.....   ...||      :|.||......:::::....:     |.|   
Human    65 VVSPEQFMKSFEHMKKSGDYYVTVVED------VTLGQIVATATLIIEHKFIHS-----CAK--- 115

  Fly    82 TWQGRYFFVEDIYVRPEHRKRGAGKRIFLEVASRAVELQCPRLEFNVLEWNPARKFYESLGAVDL 146
              :||   |||:.|..|.|.:..||.:...:...:.:|.|.::....|..|..  ||:..|    
Human   116 --RGR---VEDVVVSDECRGKQLGKLLLSTLTLLSKKLNCYKITLECLPQNVG--FYKKFG---- 169

  Fly   147 TDKEGWHYYRVEEQ 160
                    |.|.|:
Human   170 --------YTVSEE 175

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
CG4210NP_650430.1 Acetyltransf_1 65..142 CDD:278980 18/76 (24%)
GNPNAT1NP_932332.1 NAT_SF 36..174 CDD:418431 32/141 (23%)
Substrate binding. /evidence=ECO:0000269|PubMed:18675810, ECO:0000305|PubMed:18601654, ECO:0007744|PDB:3CXQ 108..111 0/2 (0%)
Substrate binding. /evidence=ECO:0000269|PubMed:18675810, ECO:0000305|PubMed:18601654, ECO:0007744|PDB:3CXQ 120..122 1/1 (100%)
Acetyl-CoA binding. /evidence=ECO:0000305|PubMed:18601654, ECO:0007744|PDB:2O28 130..135 0/4 (0%)