DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6654 and ZBTB39

DIOPT Version :9

Sequence 1:NP_650429.1 Gene:CG6654 / 41831 FlyBaseID:FBgn0038301 Length:639 Species:Drosophila melanogaster
Sequence 2:NP_055645.1 Gene:ZBTB39 / 9880 HGNCID:29014 Length:712 Species:Homo sapiens


Alignment Length:308 Identity:90/308 - (29%)
Similarity:123/308 - (39%) Gaps:56/308 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   329 YHCDRCNAGFAVEKSLMIHRRQKGCINRNYKCNECEKVFVSPDHLAEHQ------ASHGAHNCPE 387
            :.||.|...|..:..|.:|||. |....|        :.|.|:.....:      |:.....|..
Human   400 FSCDMCETKFFTQWQLTLHRRD-GIFENN--------IIVHPNDPLPGKLGLFSGAASPELKCAA 455

  Fly   388 CGIRCDSKEALSK--HMVQGH---KRNLRNQ-CNICQKVFTMLSTLRDHMRIHTGEKPFVCNICG 446
            ||      :.|:|  |:|:||   ..||:.| |::|.:....|.:|..|...|.|...|.|::|.
Human   456 CG------KVLAKDFHVVRGHILDHLNLKGQACSVCDQRHLNLCSLMWHTLSHLGISVFSCSVCA 514

  Fly   447 KSFTQNANLRQHKLRHS--ETKSFKCELCPHSFVTKAELTSHARTHTGDKPFECEVCL-ARFTTS 508
            .||.....|.:|...|.  |...|.|.||..||.::|....|...|      :|...| ||  ..
Human   515 NSFVDWHLLEKHMAVHQSLEDALFHCRLCSQSFKSEAAYRYHVSQH------KCNSGLDAR--PG 571

  Fly   509 CSL---AKHKRK---------------HTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCP 555
            ..|   |..|||               ..|...|:|.:|..||...:....|||.||||:||.|.
Human   572 FGLQHPALQKRKLPAEEFLGEELALQGQPGNSKYSCKVCGKRFAHTSEFNYHRRIHTGEKPYQCK 636

  Fly   556 FCSKTFTQRGDCQMHQRTHQGERIYICPVCNEEFKSMPEMRSHLAGHE 603
            .|.|.|..|...:.|.:||.|..:|.|.||.....::..|..|:..|:
Human   637 VCHKFFRGRSTIKCHLKTHSGALMYRCTVCGHYSSTLNLMSKHVGVHK 684

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6654NP_650429.1 zf-AD 6..79 CDD:285071
C2H2 Zn finger 331..354 CDD:275368 9/22 (41%)
COG5048 <357..570 CDD:227381 70/245 (29%)
C2H2 Zn finger 360..380 CDD:275368 3/25 (12%)
C2H2 Zn finger 385..406 CDD:275370 7/22 (32%)
C2H2 Zn finger 414..434 CDD:275368 5/19 (26%)
zf-H2C2_2 427..451 CDD:290200 9/23 (39%)
C2H2 Zn finger 442..490 CDD:275368 16/49 (33%)
C2H2 Zn finger 470..487 CDD:275368 6/16 (38%)
zf-H2C2_2 482..507 CDD:290200 6/25 (24%)
C2H2 Zn finger 498..518 CDD:275368 9/38 (24%)
zf-H2C2_2 510..534 CDD:290200 10/41 (24%)
C2H2 Zn finger 526..546 CDD:275368 7/19 (37%)
zf-H2C2_2 539..563 CDD:290200 13/23 (57%)
C2H2 Zn finger 554..574 CDD:275368 6/19 (32%)
C2H2 Zn finger 582..602 CDD:275368 5/19 (26%)
ZBTB39NP_055645.1 BTB 20..119 CDD:306997
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 129..162
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 176..224
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 236..260
C2H2 Zn finger 453..474 CDD:275368 9/26 (35%)
C2H2 Zn finger 482..502 CDD:275368 5/19 (26%)
C2H2 Zn finger 510..530 CDD:275368 6/19 (32%)
C2H2 Zn finger 540..560 CDD:275368 7/19 (37%)
C2H2 Zn finger 607..627 CDD:275368 7/19 (37%)
zf-H2C2_2 619..643 CDD:316026 12/23 (52%)
C2H2 Zn finger 635..655 CDD:275368 6/19 (32%)
C2H2 Zn finger 663..683 CDD:275368 5/19 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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