DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6654 and ZBTB24

DIOPT Version :9

Sequence 1:NP_650429.1 Gene:CG6654 / 41831 FlyBaseID:FBgn0038301 Length:639 Species:Drosophila melanogaster
Sequence 2:NP_055612.2 Gene:ZBTB24 / 9841 HGNCID:21143 Length:697 Species:Homo sapiens


Alignment Length:517 Identity:133/517 - (25%)
Similarity:221/517 - (42%) Gaps:95/517 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   169 ILQVQGNLKDEKEVVFTQTNVIYEGDDHELEQQIRECNLAIFEGVDNEAEIITV----------- 222
            |..::|.:.|...::.   ..||.|..|..|:..        |.:...|:.:.|           
Human    76 IYMLEGMVADTFGILL---EFIYTGYLHASEKST--------EQILATAQFLKVYDLVKAYTDFQ 129

  Fly   223 ---TAPQVTTRKSAAK---LLTQQENDKHQTPVGSKEEARELEKEQVPQSAKRTSRRR------- 274
               ::|:.||..:|..   :::.::||..:...|..::...|::|:...:|:...:.|       
Human   130 NNHSSPKPTTLNTAGAPVVVISNKKNDPPKRKRGRPKKVNTLQEEKSELAAEEEIQLRVNNSVQN 194

  Fly   275 ----------GVVKQDVPATPPSDAEPSPKQHRLGTQRKLSAPRAGTVNGPSTTSGAAT------ 323
                      ||:.:.:.|....::||:.:..|   :.::...:....: |.|..|.|:      
Human   195 RQNFVVKGDSGVLNEQIAAKEKEESEPTCEPSR---EEEMPVEKDENYD-PKTEDGQASQSRYSK 255

  Fly   324 --------TPELKYHCDRCNAGFAVEKSLMIHRRQKGCINRNYKCNECEKVFVSPDHLAEHQASH 380
                    ..:.|...|:.:.|.|  |.:...|::.|  ....:|.:|.|||.....||.||.||
Human   256 RRIWRSVKLKDYKLVGDQEDHGSA--KRICGRRKRPG--GPEARCKDCGKVFKYNHFLAIHQRSH 316

  Fly   381 GAHNCPECGIRCDSKEALSKHMVQGHKRNLRNQCNICQKVFTMLSTLRDHMRIHTGEKPFVCNIC 445
            ..                        :|..:  ||.|.|.|....:|:.|.|:||||:|:.|.:|
Human   317 TG------------------------ERPFK--CNECGKGFAQKHSLQVHTRMHTGERPYTCTVC 355

  Fly   446 GKSFTQNANLRQHKLRHSETKSFKCELCPHSFVTKAELTSHARTHTGDKPFECEVCLARFTTSCS 510
            .|:.|...:|.:|...||..|||.|:.|...|....:|.||.|.|||....||:.|..:|.....
Human   356 SKALTTKHSLLEHMSLHSGQKSFTCDQCGKYFSQNRQLKSHYRVHTGHSLPECKDCHRKFMDVSQ 420

  Fly   511 LAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKTFTQRGDCQMHQRTHQ 575
            |.||.|.||||:|:.|::|...|||.:.|:.|.|.|.||:||.|..|.|:|:.....:.|...|.
Human   421 LKKHLRTHTGEKPFTCEICGKSFTAKSSLQTHIRIHRGEKPYSCGICGKSFSDSSAKRRHCILHT 485

  Fly   576 GERIYICPVCNEEFKSMPEMRSHLAGH--EQHDKRLVHFTFLSNKENGSGALEEELNEMTES 635
            |::.:.||.||.:|..:..:::||..|  |:|.......:..||.|.....|:.:..:::.|
Human   486 GKKPFSCPECNLQFARLDNLKAHLKIHSKEKHASDASSISGSSNTEEVRNILQLQPYQLSTS 547

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6654NP_650429.1 zf-AD 6..79 CDD:285071
C2H2 Zn finger 331..354 CDD:275368 6/22 (27%)
COG5048 <357..570 CDD:227381 76/212 (36%)
C2H2 Zn finger 360..380 CDD:275368 9/19 (47%)
C2H2 Zn finger 385..406 CDD:275370 0/20 (0%)
C2H2 Zn finger 414..434 CDD:275368 8/19 (42%)
zf-H2C2_2 427..451 CDD:290200 11/23 (48%)
C2H2 Zn finger 442..490 CDD:275368 18/47 (38%)
C2H2 Zn finger 470..487 CDD:275368 5/16 (31%)
zf-H2C2_2 482..507 CDD:290200 11/24 (46%)
C2H2 Zn finger 498..518 CDD:275368 7/19 (37%)
zf-H2C2_2 510..534 CDD:290200 11/23 (48%)
C2H2 Zn finger 526..546 CDD:275368 8/19 (42%)
zf-H2C2_2 539..563 CDD:290200 12/23 (52%)
C2H2 Zn finger 554..574 CDD:275368 5/19 (26%)
C2H2 Zn finger 582..602 CDD:275368 7/19 (37%)
ZBTB24NP_055612.2 BTB 27..133 CDD:306997 11/67 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 131..176 9/44 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 209..254 8/48 (17%)
C2H2 Zn finger 296..316 CDD:275368 9/19 (47%)
COG5048 <321..480 CDD:227381 64/160 (40%)
C2H2 Zn finger 324..344 CDD:275368 8/19 (42%)
C2H2 Zn finger 352..372 CDD:275368 6/19 (32%)
C2H2 Zn finger 380..400 CDD:275368 7/19 (37%)
C2H2 Zn finger 408..428 CDD:275368 7/19 (37%)
C2H2 Zn finger 436..456 CDD:275368 8/19 (42%)
C2H2 Zn finger 464..480 CDD:275368 4/15 (27%)
C2H2 Zn finger 492..512 CDD:275368 7/19 (37%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 652..697
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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