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Protein Alignment CG6654 and ZNF665

DIOPT Version :9

Sequence 1:	NP_650429.1	Gene:	CG6654 / 41831	FlyBaseID:	FBgn0038301	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_001340387.1	Gene:	ZNF665 / 79788	HGNCID:	25885	Length:	706	Species:	Homo sapiens

Alignment Length:	554	Identity:	157/554 - (28%)
Similarity:	224/554 - (40%)	Gaps:	135/554 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 VSISCPVATTD----------QAVQTTSWEPDRCTASVQTDAVTTTDAEQNTSLIKSTISVDLDY 146
            :.|||....||          :|..|...|.   ..|..|..::..:.::||            |
Human    75 LDISCKCVNTDLPPKGKNNMGEAFYTVKLER---LESCDTVGLSFQEVQKNT------------Y 124

  Fly   147 EGEGEVFDYELPDEPVEKTTSLILQVQGNLKDEKEVVFTQTNVIYEGDDHELEQQIRECNLAIFE 211
            :     |:.:..|:.....|.|:||.: ||...:    .|.:....|:.| :|.|:
Human   125 D-----FECQWKDDEGNYKTVLMLQKE-NLPGRR----AQRDRRAAGNRH-IENQL--------- 169

  Fly   212 GVDNEAEIITVTAPQVTTRKSAAKLLTQQENDKHQTPVGSKEEARELEKEQVPQSAKRTSRRRGV 276
            ||..::.:     |::...:...|:....:.:|.....|...:..|..| ...|:::.||.:|
Human   170 GVSFQSHL-----PELQQFQHEGKIYEYNQVEKSPNNRGKHYKCDECGK-VFSQNSRLTSHKR-- 226

  Fly   277 VKQDVPATPPSDAEPSPKQHRLGTQRKLSAPRAGTVNGPSTTSGAATTPELKYHCDRCNAGFAVE 341
                                                         ..|.|..|.|::|...|.|.
Human   227 ---------------------------------------------IHTGEKPYQCNKCGKAFTVR 246

  Fly   342 KSLMIHR-RQKGCINRNYKCNECEKVFVSPDHLAEHQASHGA---HNCPECG--IRCDSKEALSK 400
            .:|.||: ...|  .:.||||||.|||..|.:||.||..|..   :.|.|||  .|..||  |:.
Human   247 SNLTIHQVIHTG--EKPYKCNECGKVFSQPSNLAGHQRIHTGEKPYKCNECGKAFRAHSK--LTT 307

  Fly   401 HMV-----------------------QGHKR----NLRNQCNICQKVFTMLSTLRDHMRIHTGEK 438
            |.|                       ..|:|    ....:||.|.|.|::.|:|..|..||||||
Human   308 HQVIHTGEKPYKCKECGKCFTQNSHLASHRRIHTGEKPYKCNECGKAFSVRSSLTTHQTIHTGEK 372

  Fly   439 PFVCNICGKSFTQNANLRQHKLRHSETKSFKCELCPHSFVTKAELTSHARTHTGDKPFECEVCLA 503
            |:.||.|||.|..|:.|.:|:..|:..|.:||..|..:|...:.||.|...|||:|||:|..|:.
Human   373 PYKCNECGKVFRHNSYLAKHRRIHTGEKPYKCNECGKAFSMHSNLTKHQIIHTGEKPFKCNECVK 437

  Fly   504 RFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKTFTQRGDCQ 568
            .||....||.|:|.||||:||.||.|...|:..:.|..|:..||||:||.|..|.|.|||.....
Human   438 VFTQYSHLANHRRIHTGEKPYRCDECGKAFSVRSSLTTHQAIHTGEKPYKCNDCGKVFTQNSHLA 502

  Fly   569 MHQRTHQGERIYICPVCNEEFKSMPEMRSHLAGH 602
            .|:..|.||:.|.|..|.:.|....::..|...|
Human   503 SHRGIHSGEKPYKCDECGKAFSQTSQLARHWRVH 536

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.