DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG6654 and ZNF141

DIOPT Version :9

Sequence 1:NP_650429.1 Gene:CG6654 / 41831 FlyBaseID:FBgn0038301 Length:639 Species:Drosophila melanogaster
Sequence 2:XP_016864080.1 Gene:ZNF141 / 7700 HGNCID:12926 Length:534 Species:Homo sapiens


Alignment Length:450 Identity:128/450 - (28%)
Similarity:184/450 - (40%) Gaps:109/450 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   191 YEGDDHELEQ------QIRECNLAIFEGVDNE-AEIITVTAPQVTTRKSAAKLLTQQENDKHQTP 248
            ||...|:..|      .:.||.|.  :|..|| .|.::.|..::...|::.|::::..|      
Human   163 YEKCGHDNLQLRKGCKSLNECKLQ--KGGYNEFNECLSTTQSKILQCKASVKVVSKFSN------ 219

  Fly   249 VGSKEEARELEKEQVPQSAKRTSRRRGVVKQDVPATPPSDAEPSPKQHRLGTQRKLSAPRAGTVN 313
             .:|.:.|...::...:..|...:...:                       ||.|:.  .||   
Human   220 -SNKRKTRHTGEKHFKECGKSFQKFSHL-----------------------TQHKVI--HAG--- 255

  Fly   314 GPSTTSGAATTPELKYHCDRCNAGFAVEKSLM------IHRRQKGCINRNYKCNECEKVFVSPDH 372
                        |..|.|:.|  |.|.:.||:      ||..:|     .:.|.||..:|.:..|
Human   256 ------------EKPYTCEEC--GKAFKWSLIFNEHKRIHTGEK-----PFTCEECGSIFTTSSH 301

  Fly   373 LAEHQASHGA---HNCPECGIRCDSKEALSKHMVQGHKRNLRNQCNICQKVFTMLSTLRDHMRIH 434
            .|:|:..|..   :.|.|||                             |.|...:||..|.|||
Human   302 FAKHKIIHTGEKPYKCEECG-----------------------------KAFNRFTTLTKHKRIH 337

  Fly   435 TGEKPFVCNICGKSFTQNANLRQHKLRHSETKSFKCELCPHSFVTKAELTSHARTHTGDKPFECE 499
            .||||..|..|.|.||.::|..:||..|:..|.:|||.|..:|.....||.|.|.|||:||:.||
Human   338 AGEKPITCEECRKIFTSSSNFAKHKRIHTGEKPYKCEECGKAFNRSTTLTKHKRIHTGEKPYTCE 402

  Fly   500 VCLARFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKTFTQR 564
            .|...|..|..|.:||:.|||||||.||.|...|....||..|::.||||:||.|..|.|.|.:.
Human   403 ECGKAFRQSSKLNEHKKVHTGERPYKCDECGKAFGRSRVLNEHKKIHTGEKPYKCEECGKAFRRS 467

  Fly   565 GDCQMHQRTHQGERIYICPVCNEEFKSMPEMRSHLAGH--------EQHDKRLVHFTFLS 616
            .|...|::.|..::.|.|..|::.||....:..|...|        :..||....|:.|:
Human   468 TDRSQHKKIHSADKPYKCKECDKAFKQFSLLSQHKKIHTVDKPYKCKDCDKAFKRFSHLN 527

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6654NP_650429.1 zf-AD 6..79 CDD:285071
C2H2 Zn finger 331..354 CDD:275368 9/28 (32%)
COG5048 <357..570 CDD:227381 81/215 (38%)
C2H2 Zn finger 360..380 CDD:275368 7/19 (37%)
C2H2 Zn finger 385..406 CDD:275370 4/20 (20%)
C2H2 Zn finger 414..434 CDD:275368 6/19 (32%)
zf-H2C2_2 427..451 CDD:290200 13/23 (57%)
C2H2 Zn finger 442..490 CDD:275368 19/47 (40%)
C2H2 Zn finger 470..487 CDD:275368 6/16 (38%)
zf-H2C2_2 482..507 CDD:290200 13/24 (54%)
C2H2 Zn finger 498..518 CDD:275368 8/19 (42%)
zf-H2C2_2 510..534 CDD:290200 13/23 (57%)
C2H2 Zn finger 526..546 CDD:275368 7/19 (37%)
zf-H2C2_2 539..563 CDD:290200 12/23 (52%)
C2H2 Zn finger 554..574 CDD:275368 6/19 (32%)
C2H2 Zn finger 582..602 CDD:275368 5/19 (26%)
ZNF141XP_016864080.1 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.000

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