DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6654 and zbtb8a

DIOPT Version :9

Sequence 1:NP_650429.1 Gene:CG6654 / 41831 FlyBaseID:FBgn0038301 Length:639 Species:Drosophila melanogaster
Sequence 2:NP_001035340.2 Gene:zbtb8a / 678523 ZFINID:ZDB-GENE-060421-5153 Length:459 Species:Danio rerio


Alignment Length:592 Identity:111/592 - (18%)
Similarity:185/592 - (31%) Gaps:237/592 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    72 SSRTLRQLLPNALPEEPDSKVSISCPVATTDQAVQTTSWEPDRCTASVQTDAVTTTDAEQNTSLI 136
            ||...|.||.....:..|| ||.|..|           :.||..|  :..|.:.:...|.|:|.:
Zfish    75 SSGYFRMLLTQGAKDTVDS-VSASFDV-----------FSPDIFT--IILDFIYSGQLELNSSNV 125

  Fly   137 KSTISVDLDYEGEGEVFDY---------ELPDEPVEKTTSLILQVQGNLKDEKEVVFTQTNVIYE 192
            ...:|. ..|....:|..|         |:..:..::...|.|....:|:|.:|.....:|:   
Zfish   126 IEVMSA-ASYLQMNDVISYCKAFIKSFLEISTKEDDENRYLCLSENSSLQDRRESTIEPSNM--- 186

  Fly   193 GDDHELEQQIRECNLAIFEGVDNEAEIITVTAPQVTTRKSAAKLLTQQENDKHQTPVGSKEEARE 257
                        |::::                     .|.::|..:::.|..            
Zfish   187 ------------CDVSM---------------------SSQSRLWDEEQEDDQ------------ 206

  Fly   258 LEKEQVPQSAKRTSRRRGVVKQDVPATPPSDAEPSPKQHRLGTQRKLSAPRAGTVNGPSTTSGAA 322
                  ||             :|...|.|   :||..||                |.|     |.
Zfish   207 ------PQ-------------EDFGGTSP---QPSGLQH----------------NSP-----AQ 228

  Fly   323 TTPELKYHCDRCNAGFAVEKSLMIHRRQKGCINRNYKCNECEKVFVSPDHLAEHQ--ASHGAHNC 385
            ::.|.:|            .|::..||::|    :.|.....::......|.:.|  .||     
Zfish   229 SSLEEQY------------SSVLPERRRRG----SRKRTASSRLVAEDTSLIDLQGVVSH----- 272

  Fly   386 PECGIRCDSKEALSKHMVQGHKRNLRNQCNICQKVFTMLSTLRDHMRIHTGEKPFVCNICGKSFT 450
              |..:.|...|           ||                            |.:..:.| .|.
Zfish   273 --CSQKADELYA-----------NL----------------------------PSIVGVVG-MFN 295

  Fly   451 QNANLRQHKLRHSETKSFKCELCPHSFVTKAELTSHARTHTGDKPFECEVCLARFTTSCSLAKHK 515
            ::|         :.:..:||..|.|:...||:|..|.|                    |      
Zfish   296 KDA---------TPSMRYKCPFCTHTVKRKADLKRHLR--------------------C------ 325

  Fly   516 RKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKTFTQRGDCQMHQRTHQGERIY 580
              |||||||.|..|..|||.|..|::|..|....|..||..|.:..|:...    :...:|.|.|
Zfish   326 --HTGERPYPCQACSKRFTRLEHLRSHFETIHQARKLVCRKCKRHVTEVSG----RVVSEGTRKY 384

  Fly   581 -ICPVCNEEFKSMPEMRSHLAGHEQHDKRLV----------HFTFLSN-----KENGSGALEEEL 629
             :|.||.:|......:.....|:|..:..|:          ..|::.:     :::|:..:.:|:
Zfish   385 RLCDVCIQESGYNDLITDETDGNEDKEGLLLGVDEDMSENRQITWVMDDDDLAEDSGADLIIQEV 449

  Fly   630 NEMTESA 636
            ::..|.|
Zfish   450 DDSDEEA 456

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6654NP_650429.1 zf-AD 6..79 CDD:285071 3/6 (50%)
C2H2 Zn finger 331..354 CDD:275368 4/22 (18%)
COG5048 <357..570 CDD:227381 45/214 (21%)
C2H2 Zn finger 360..380 CDD:275368 2/21 (10%)
C2H2 Zn finger 385..406 CDD:275370 3/20 (15%)
C2H2 Zn finger 414..434 CDD:275368 0/19 (0%)
zf-H2C2_2 427..451 CDD:290200 3/23 (13%)
C2H2 Zn finger 442..490 CDD:275368 12/47 (26%)
C2H2 Zn finger 470..487 CDD:275368 6/16 (38%)
zf-H2C2_2 482..507 CDD:290200 3/24 (13%)
C2H2 Zn finger 498..518 CDD:275368 1/19 (5%)
zf-H2C2_2 510..534 CDD:290200 10/23 (43%)
C2H2 Zn finger 526..546 CDD:275368 8/19 (42%)
zf-H2C2_2 539..563 CDD:290200 7/23 (30%)
C2H2 Zn finger 554..574 CDD:275368 3/19 (16%)
C2H2 Zn finger 582..602 CDD:275368 4/19 (21%)
zbtb8aNP_001035340.2 BTB 44..149 CDD:279045 22/88 (25%)
BTB 55..152 CDD:197585 22/91 (24%)
COG5048 304..>357 CDD:227381 26/80 (33%)
C2H2 Zn finger 306..326 CDD:275368 9/47 (19%)
zf-H2C2_2 318..343 CDD:290200 15/52 (29%)
C2H2 Zn finger 334..355 CDD:275368 9/20 (45%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
00.000

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