DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6654 and CG18764

DIOPT Version :9

Sequence 1:NP_650429.1 Gene:CG6654 / 41831 FlyBaseID:FBgn0038301 Length:639 Species:Drosophila melanogaster
Sequence 2:NP_652712.2 Gene:CG18764 / 59239 FlyBaseID:FBgn0042205 Length:409 Species:Drosophila melanogaster


Alignment Length:583 Identity:113/583 - (19%)
Similarity:188/583 - (32%) Gaps:211/583 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 CLTCLSSTGPLL------SIYDGGSGSCLADMIREFTKTKPRRNDNLPEKVCLSCLSEISNCYTF 65
            |.||    |.::      :::...:...|.| |...|.|....:..||..:|..|..:::....|
  Fly     5 CRTC----GSIIYNKMPKNLFHIENEKMLQD-INLVTGTTLHNDPELPSSICACCTLDLNQAILF 64

  Fly    66 KIKCENSSRTL--RQLLPNALPEEPDSKVSISCPVATTDQAVQTTSWEPDRCTASVQTDAVTTTD 128
            :.:|..:.:.|  |:..|.|.....|.:...|.|                        |.:....
  Fly    65 RERCILTQKQLVHRRRSPEAKEPAEDVEEMASPP------------------------DCLNDPF 105

  Fly   129 AEQNTSLIKSTISVDLDYEGEGEVFDYELPD----EPVEKTTSLILQVQGNLKDEKEVVFTQTNV 189
            .|.:..:::|...| ||::.:..   ::|.:    :.||...:        |:|..||.      
  Fly   106 GEVDEYIVESPEEV-LDHDSDAH---HDLDEDNYIDSVEDVDA--------LQDMAEVA------ 152

  Fly   190 IYEGDDHELEQQIRECNLAIFEGVDNEAEIITVTAPQVTTRKSAAKLLTQQENDKHQTPV-GS-- 251
              |.|..::|        ::...|..|.|             |.....:..:|:.:..|. ||  
  Fly   153 --EEDSQDVE--------SLISSVQKELE-------------SICNDDSNSDNNDYMEPQNGSYF 194

  Fly   252 KEEARELEKEQVPQSAKRTSRRRGVVKQDVPATPPSDAEPSPKQHRLGTQRKLSAPRAGTVNGPS 316
            .|...|.|....|.:                        |.|:          |...||....|:
  Fly   195 NETINEYEVSSNPNT------------------------PLPE----------SKSAAGRSTKPA 225

  Fly   317 TTSGAATTPELKYHCDRCNAGFAVEKSLMIHRRQKGCINRNYKCNECEKVFVSPDHLAEHQASHG 381
            ||.     |:.|                                    |.:|:..::.|.|    
  Fly   226 TTK-----PKRK------------------------------------KQYVTWKNMTEEQ---- 245

  Fly   382 AHNCPECGIRCDSKEALSKHMVQGHKRNLRNQCNICQKVFTMLSTLRDHMRIHTGEKPFVCNICG 446
                                :::..:...:.:|                          ||..||
  Fly   246 --------------------IIERKRLQRKREC--------------------------VCEQCG 264

  Fly   447 KSFTQNANLRQHKLRHSETKSFKCELCPHSFVTKAELTSHAR-THTGDKPFECEVCLARFTTSCS 510
            :.||..:|.:.|.|||:..|:|.|:.|...|.|...:|.|.| .|.|:||::|..|...|..|.:
  Fly   265 RQFTDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHLMTLHQRIIHQGEKPYDCRFCTKSFHNSNT 329

  Fly   511 LAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKTFTQRGDCQMHQRT 573
            ...|:|.||..:||:|..|...|.:.:..|.|...|||.|.:.|..|.::|.:....:.|.|:
  Fly   330 RLIHERTHTNAKPYSCHHCDKCFKSASGRKRHELIHTGVRAFACTICKQSFQRNTHLKAHLRS 392

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6654NP_650429.1 zf-AD 6..79 CDD:285071 17/79 (22%)
C2H2 Zn finger 331..354 CDD:275368 0/22 (0%)
COG5048 <357..570 CDD:227381 51/213 (24%)
C2H2 Zn finger 360..380 CDD:275368 4/19 (21%)
C2H2 Zn finger 385..406 CDD:275370 0/20 (0%)
C2H2 Zn finger 414..434 CDD:275368 1/19 (5%)
zf-H2C2_2 427..451 CDD:290200 5/23 (22%)
C2H2 Zn finger 442..490 CDD:275368 19/48 (40%)
C2H2 Zn finger 470..487 CDD:275368 5/16 (31%)
zf-H2C2_2 482..507 CDD:290200 10/25 (40%)
C2H2 Zn finger 498..518 CDD:275368 6/19 (32%)
zf-H2C2_2 510..534 CDD:290200 8/23 (35%)
C2H2 Zn finger 526..546 CDD:275368 5/19 (26%)
zf-H2C2_2 539..563 CDD:290200 9/23 (39%)
C2H2 Zn finger 554..574 CDD:275368 5/20 (25%)
C2H2 Zn finger 582..602 CDD:275368
CG18764NP_652712.2 zf-AD 4..75 CDD:214871 15/74 (20%)
C2H2 Zn finger 260..280 CDD:275368 8/19 (42%)
zf-H2C2_2 272..297 CDD:290200 10/24 (42%)
C2H2 Zn finger 288..309 CDD:275368 7/20 (35%)
C2H2 Zn finger 317..337 CDD:275368 6/19 (32%)
C2H2 Zn finger 345..365 CDD:275368 5/19 (26%)
C2H2 Zn finger 373..391 CDD:275368 4/17 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 84 1.000 Inparanoid score I1804
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.960

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