DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG6654 and ZNF692

DIOPT Version :9

Sequence 1:NP_650429.1 Gene:CG6654 / 41831 FlyBaseID:FBgn0038301 Length:639 Species:Drosophila melanogaster
Sequence 2:XP_011542525.1 Gene:ZNF692 / 55657 HGNCID:26049 Length:625 Species:Homo sapiens


Alignment Length:334 Identity:89/334 - (26%)
Similarity:132/334 - (39%) Gaps:64/334 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   228 TTRKSAAKLLTQQENDKHQTPVGSKEEARELEKE--QVPQSAKRTSRRRGVVKQDVPATPPSDAE 290
            |||:|.....|            |.:|..:||.|  :..|.|:..|.     :.|.|...||...
Human   293 TTRRSWCSEAT------------SGQELADLESEHDERTQEARLPSS-----EPDAPRLLPSPVT 340

  Fly   291 PSPKQHRL-GTQRKLSAPRAGTVNGPSTTSGAATTP-ELKYHCDRCNAGFAVEKSLMIHRRQKGC 353
            .:||:... .....||:|.|......|:.|..|..| |::..........|.:::          
Human   341 CTPKEGETPPAPAALSSPLAVPALSASSLSSRAPPPAEVRVQPQLSRTPQAAQQT---------- 395

  Fly   354 INRNYKCNECEKVFVSPDHLAEHQASHG--AHNCPECGIRCDSKEALSKHMVQGHKRNLRNQCNI 416
                                 |..||.|  |.:.|......|:.:...|.:.:..||.|. .|:.
Human   396 ---------------------EALASTGSQAQSAPTPAWDEDTAQIGPKRIRKAAKRELM-PCDF 438

  Fly   417 --CQKVFTMLSTLRDHMRI-HTGEKPFVC--NICGKSFTQNANLRQHKLRHSETKSFKCELCPHS 476
              |.::|:....|..|.:. |..:|.|.|  ..|||||....:|::|...||:|:.:.||.|..|
Human   439 PGCGRIFSNRQYLNHHKKYQHIHQKSFSCPEPACGKSFNFKKHLKEHMKLHSDTRDYICEFCARS 503

  Fly   477 FVTKAELTSHARTHTGDKPFECEVCLARFTTSCSLAKHKRKH---TGERPYACDLCPMRFTALNV 538
            |.|.:.|..|.|.|||:||.:||:|........||..|:|||   .....:.|:.|..||...:.
Human   504 FRTSSNLVIHRRIHTGEKPLQCEICGFTCRQKASLNWHQRKHAETVAALRFPCEFCGKRFEKPDS 568

  Fly   539 LKNHR-RTH 546
            :..|| ::|
Human   569 VAAHRSKSH 577

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6654NP_650429.1 zf-AD 6..79 CDD:285071
C2H2 Zn finger 331..354 CDD:275368 1/22 (5%)
COG5048 <357..570 CDD:227381 60/201 (30%)
C2H2 Zn finger 360..380 CDD:275368 2/19 (11%)
C2H2 Zn finger 385..406 CDD:275370 3/20 (15%)
C2H2 Zn finger 414..434 CDD:275368 5/22 (23%)
zf-H2C2_2 427..451 CDD:290200 11/26 (42%)
C2H2 Zn finger 442..490 CDD:275368 20/49 (41%)
C2H2 Zn finger 470..487 CDD:275368 7/16 (44%)
zf-H2C2_2 482..507 CDD:290200 11/24 (46%)
C2H2 Zn finger 498..518 CDD:275368 7/19 (37%)
zf-H2C2_2 510..534 CDD:290200 9/26 (35%)
C2H2 Zn finger 526..546 CDD:275368 6/20 (30%)
zf-H2C2_2 539..563 CDD:290200 3/9 (33%)
C2H2 Zn finger 554..574 CDD:275368
C2H2 Zn finger 582..602 CDD:275368
ZNF692XP_011542525.1 zf-C2H2 465..489 CDD:278523 9/23 (39%)
C2H2 Zn finger 467..489 CDD:275368 8/21 (38%)
COG5048 490..>591 CDD:227381 32/88 (36%)
zf-C2H2 495..517 CDD:278523 9/21 (43%)
C2H2 Zn finger 497..517 CDD:275368 9/19 (47%)
zf-H2C2_2 509..534 CDD:290200 11/24 (46%)
C2H2 Zn finger 525..545 CDD:275368 7/19 (37%)
C2H2 Zn finger 556..577 CDD:275368 6/20 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24390
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

Return to query results.
Submit another query.